摘要
目的:探讨育龄期患多囊卵巢综合征的不孕症患者的睡眠状况对多囊卵巢综合征发病的影响。方法:选取2017年3月至2019年12月华润武钢总医院妇产科收治的不孕症患者600例作为研究对象,按照是否同时患有多囊卵巢综合征分为对照组和观察组,每组300例。观察组为育龄期患多囊卵巢综合征的不孕症患者,对照组为同期未患多囊卵巢综合征的不孕症患者。收集患者的临床诊治资料并对相关资料展开回顾性的整合分析,探讨接受治疗前1个月内2组患者的睡眠状况评分,并进行单因素及多因素回归分析。结果:2组患者的匹兹堡睡眠质量指数量表评分对照,差异有统计学意义(P<0.05),相较于对照组,观察组的匹兹堡睡眠质量指数量表评分明显增高,差异有统计学意义(P<0.05);2组的年龄、体质量、身高、BMI、学历等因素对照,差异无统计学意义(P>0.05);2组的自由职业、睡眠障碍等因素对照,差异有统计学意义(P<0.05);BMI、睡眠障碍等因素是多囊卵巢综合征发病的独立高危因素,自由职业是多囊卵巢综合征发病的独立保护因素。结论:育龄期患多囊卵巢综合征的不孕症患者的睡眠状况较差。对于患有不孕症的育龄期女性而言,存在睡眠障碍且BMI偏高,患有多囊卵巢综合征的概率将进一步增高,而从事自由职业将在一定程度上削减多囊卵巢综合征的发生风险。
Objective:To investigate the effect of sleep status on the pathogenesis of polycystic ovary syndrome(PCOS)in infertile women with PCOS at childbearing age.Methods:A total of 600 infertile patients in the Department of Obstetrics and Gynecology of China Resources WISCO general hospital from March 2017 to December 2019 were selected as the research objects,and they were divided into the control group and the observation group according to whether they had polycystic ovary syndrome at the same time,with 300 cases in each group.The observation group was infertility patients with polycystic ovary syndrome in childbearing age,and the control group was infertility patients without polycystic ovary syndrome in the same period.The clinical diagnosis and treatment data of the patients were collected,and the related data were analyzed retrospectively.The sleep status scores of the two groups within one month before treatment were discussed,and the univariate and multivariate regression analysis were carried out.Results:The Pittsburgh sleep quality index scale scores of the two groups were significantly different(P<0.05).Compared with the control group,the Pittsburgh sleep quality index scale scores of the observation group were significantly higher(P<0.05);the age,weight,height,BMI,education and other factors of the two groups were not significantly different(P>0.05);the free occupation,sleep disorders and other factors of the two groups were not significantly different(P>0.05).In contrast,the difference was significant(P<0.05);BMI,sleep disorders and other factors were independent high-risk factors of PCOS,and freelance occupation was independent protective factors of PCOS.Conclusion:The sleep status of infertility patients with PCOS is poor.For women of childbearing age who suffer from infertility,sleep disorders and high BMI will further increase the probability of suffering from PCOS,while freelancing will reduce the risk of PCOS to a certain extent.
作者
杜鸣艳
DU Mingyan(Department of Obstetrics and Gynecology,Wuhan General Hospital,China Resources,Hubei Province,Wuhan 430080,China)
出处
《世界睡眠医学杂志》
2020年第12期2091-2093,共3页
World Journal of Sleep Medicine
