摘要
蕈样肉芽肿(MF)的临床表现复杂多变,该文报道1例少见的体癣样MF。该例患者因躯干、四肢皮疹伴瘙痒3年余就诊。专科检查提示躯干、四肢散在暗红色斑片,部分斑片中央消退,边缘呈堤状隆起,表面覆少量白色鳞屑,躯干四肢见广泛色素沉着和色素减退。经组织病理检查、免疫组织化学检查和T细胞受体(TCR)基因重排检测,诊断为MF。予口服糖皮质激素、环孢素及外用糖皮质激素软膏治疗2个月后,皮疹消退。该例提示MF皮疹多样,常漏诊误诊,怀疑此病应多次行皮肤病理检查,并进行免疫组织化学检查和TCR基因重排检测。
The clinical manifestations of mycosis fungoides are complex and variable. In this article, we reported one rare case of mycosis fungoides mimicking tinea corporis. The patient was admitted to our department because of rash and pruritus involved with the trunk and limbs for more than 3 years. Physical examination revealed the signs of extensive rash, characterized by annular erythematous scaly patches with raised borders, which was similar to tinea corporis. The patient was diagnosed with mycosis fungoides by skin histopathological examination, immunohistochemistry, and T cell receptor gene rearrangement. After two-month treatment of glucocorticoid, cyclosporine and topical drugs, the rash was significantly relieved. This case prompts that it is likely to miss the diagnosis and misdiagnose the mycosis fungoides due to diverse manifestations. The diagnosis should be confirmed by repeated skin pathological examination, immunohistochemical staining and T cell receptor gene rearrangement should be performed.
作者
钟娇娇
张静
张军民
鲁莎
马坚池
Zhong Jiaojiao;Zhang Jing;Zhang Junmin;Lu Sha;Ma Jianchi(Department of Dermatology,Sun Yat-sen Memorial Hospital of Sun Yat-sen University,Guangzhou 510120,China)
出处
《新医学》
2021年第2期141-144,共4页
Journal of New Medicine
基金
广东省医学科学技术研究基金(A2020576)。
关键词
蕈样肉芽肿
体癣
环状红斑
组织病理
色素异常
Mycosis fungoides
Tinea corporis
Erythema annularis
Histopathology
Pigmentation abnormality
