摘要
Magnesium(Mg)and its alloys as temporary medical implants with biodegradable and properly mechanical properties have been investigated for a long time.There are already three kinds of biodegradable Mg implants which are approved by Conformite Europeene(CE)or Korea Food and Drug Administration(KFDA),but not China Food and Drug Administration(CFDA,now it is National Medical Products Administration,NMPA).As we know,Chinese researchers,surgeons,and entrepreneurs have tried a lot to research and develop biodegradable Mg implants which might become other new approved implants for clinical applications.So in this review,we present the representative Mg implants of three categories,orthopedic implants,surgical implants,and intervention implants and provide an overview of current achievement in China from academic publications and Chinese patents.We would like to provide a systematic way to translate Mg and its alloy implants from experiment designs to clinical products.
基金
funded by the National Key Research and Development Program of China(No.2018YFC1106600,No.2016YFC1102400)
the Natural Science Foundation of China(NSFC No.51571142).
