摘要
目的调查乳腺癌改良根治术后和乳腺癌保乳术后患者抑郁水平随化疗疗程的变化趋势,探讨其抑郁变化的原因。方法选取我院2019年1月~2020年3月收治的行乳腺癌改良根治术和行乳腺癌保乳术的患者各60例,设为改良根治术后组和保乳术后组。收集两组患者一般资料,采用PHQ-9抑郁量表在其手术后和每次化疗前进行评估以了解其抑郁水平随化疗疗程的变化趋势。结果改良根治术后组抑郁发生率为30.00%,高于保乳术后组的18.33%;改良根治术后组抑郁评分高于保乳术后组,其抑郁变化趋势表现为于第2次化疗后抑郁水平增高,第3次化疗后逐渐下降,直至第5次化疗后与保乳术后组抑郁水平一致;保乳术后组抑郁评分低于改良根治术后组,其抑郁变化趋势随着化疗疗程的进展无明显变化(P>0.05)。结论乳腺癌改良根治术后患者与保乳术后的患者在化疗期间的抑郁水平和变化趋势不相同,应根据不同术式及不同化疗疗程给予相对应的心理干预,降低患者的抑郁水平。
Objective To investigate the trend of changes in the level of depression of patients after modified radical mastectomy and breast conserving surgery with the course of chemotherapy,and to explore the reasons for their changes in depression.Methods A total of 60 patients who underwent modified radical mastectomy and breast conserving surgery for breast cancer admitted to our hospital from January 2019 to March 2020 were selected as the modified radical mastectomy group and the breast conserving postoperative group.The general information of the two groups of patients was collected,and the PHQ-9 depression scale was used to evaluate their depression after surgery and before each chemotherapy to understand the trend of their depression level with the course of chemotherapy.Results The incidence of depression in the modified radical operation group was 30.00%,which was higher than 18.33%in the breast-conserving group;The depression score of the modified radical operation group was higher than that of the breast-conserving group,and the trend of depression changes showed that the depression level increased after the second chemotherapy,and gradually decreased after the third chemotherapy,until after the fifth chemotherapy and the breast-conserving surgery the depression level of the group was the same;the depression score of the breast-conserving group was lower than that of the modified radical operation group,and the trend of depression change did not change significantly with the progress of chemotherapy(P>0.05).Conclusion The depression level and change trend of patients after modified radical mastectomy for breast cancer and those after breast-conserving surgery are different during chemotherapy.Corresponding psychological interventions should be given according to different surgical procedures and different chemotherapy courses to reduce the level of depression in patients.
作者
向雅楠
黄洁
吴友凤
罗凤
石果
XIANG Ya-nan;HUANG Jie;WU You-feng;LUO Feng;SHI Guo(Department of Endocrine and Breast Surgery,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)
出处
《医学信息》
2021年第2期101-104,共4页
Journal of Medical Information
关键词
乳腺癌改良根治术
保乳术
化疗期间
抑郁
变化趋势
Modified radical mastectomy for breast cancer
Breast-conserving surgery
During chemotherapy
Depression
Change trend
