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维持性血液透析患者肾性贫血纠正情况及其影响因素分析 被引量:6

The renal anemia and its influencing factors in maintenance hemodialysis patients
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摘要 目的探讨维持性血液透析(MHD)患者肾性贫血纠正情况及其影响因素。方法收集2017年9月至2019年9月行MHD治疗患者188例。根据血红蛋白水平分为A、B、C、D四组,比较各组间基线水平及CRP、TSAT、SF、preALB、ALB、iIPTH、Ca^2+、P^3-、TG、TC等实验室指标的差异,分析影响肾性贫血达标的影响因素。结果preALB、ALB、TSAT水平,A组>B组>C组>D组逐渐降低,四组比较差异有统计学意义(P<0.05)。iPTH、P^3-、CRP水平,A组<B组<C组<D组逐渐升高,四组比较差异有统计学意义(P<0.05)。SF、TG、TC、Ca^2+水平,四组比较差异无统计学意义(P>0.05)。结论MHD患者肾性贫血治疗达标率较低,透前CRP、TSAT、preALB、ALB、iPTH、p-是MHD患者贫血不达标的影响因素。 Objective To analyse the correction of renal anemia in maintenance hemodialysis patients and explore its influencing factor.Methods 188 cases of maintenance hemodialysis in Zhejiang medical&health group Hangzhou Hospital and Haining People's Hospital from September 2017 to September 2019 were selected.According to the level of hemoglobin,the patients in group A were divided into four groups:57 cases with Hb(>110 g/L)in group A,57 cases with lOOg/L(<110 g/L)in group B,48 cases with 90g/L(<100g/L)in group C and 26 cases with 90 g/L in group D.The baseline levels and laboratory indexes such as CRP,TSAT,SF,preALB,ALB,iPTH,Ca^2+,P^3-,TG and TC were compared among the groups,and the influencing factors of renal anemia were analyzed.Results PreALB,ALB and TSAT in each group decreased gradually in group A>group B>group C>group D,with significant difference(P<0.05).IPTH,P^3-,CRP in each group were gradually increased in group A<group B<group C<group D,with significant difference(P<0.05).There was no significant difference in each group of SF,TG,TC and Ca^2+(P<0.05).Conclusion The rate of anemia treatment in maintenance hemodialysis patients is low.CRP,TSAT,preALB,ALB,iPTH,P3-before dialysis are the influencing factors of anemia failure in maintenance hemodialysis patients.
作者 平嘉溜 任颖斌 赵湘 Ping Jialiu
出处 《浙江临床医学》 2021年第1期26-28,共3页 Zhejiang Clinical Medical Journal
基金 浙江省自然科学基金资助项目(LY16H05004) 浙江省科技厅公益项目(2015C33204)。
关键词 维持性血液透析 肾性贫血 影响因素 Maintenance hemodialysis Renal anemia Influence factor
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