摘要
颈源性高血压(CHBP)指颈椎病变引起的高血压,好发于中青年人群,药物是目前治疗该疾病的有效方法,但因CHBP具有隐匿性及药物的潜在危害而导致临床诊疗有一定难度,因此探索CHBP发病机制、寻找有效的治疗方法具有重要意义。本文分析了CHBP的发病原因及病理机制,得出颈部肌肉劳损诱发交感神经兴奋、椎动脉血管被重塑后硬化是诱发CHBP并维持血压持续升高的病理基础;后期颈椎退变加重导致椎动脉持续受压,是CHBP的神经调节机制之一。
Cervical hypertension(CHBP)is a kind of high blood pressure caused by cervical spondylopathy,which is common in young and middle-aged people.At present,drug is an effective method for treating CHBP.However,because of the concealment of CHBP and the potential harm of drug use,it has been plaguing the clinic.Therefore,it is of great significance to explore the pathogenesis of CHBP and explore effective treatment methods of CHBP.This article analyzes the pathogenesis and pathological mechanism of CHBP,and concludes that cervical muscle strain induces sympathetic nerve excitement,and the vertebral artery blood vessel is remodeled and sclerosis is the pathological basis for inducing the formation of CHBP and maintaining the continuous increasing of blood pressure.Later degeneration of the cervical spine worsens eventually leading to continued compression of the vertebral artery which formed part of the CHBP neuromodulation mechanism.
作者
于娟
赵晓平
范小璇
王凯
王欢
杨永锋
马思田
YU Juan;ZHAO Xiaoping;FAN Xiaoxuan;WANG Kai;WANG Huan;YANG Yongfeng;MA Sitian(The First Clinical Medical College,Shaanxi University of Traditional Chinese Medicine,Xianyang 712000,China)
出处
《实用心脑肺血管病杂志》
2021年第1期128-133,共6页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金
国家重点研发计划项目(2017YFC1703500,2017YFC1703502)
陕西省重点研发计划项目(2019ZDLSF04-06-01)
陕西省中医脑病临床医学研究中心建设项目(201704)
陕西中医药大学学科创新团队建设项目(2019-YL15)。
关键词
颈源性高血压
椎动脉型颈椎病
动脉硬化
发病机制
综述文献
Cervical hypertension
Cervical spondylosis of vertebral artery type
Arteriosclerosis
Pathogenesy
Review literature
