摘要
目的探讨分析2型糖尿病下肢血管病变发生率及其危险因素。方法选择通州湾三余人民医院于2018年1月至2020年1月收治的2型糖尿病患者(n=196)为研究对象,对所有患者实施超声多普勒扫描检查,研究下肢血管病变发生率。并根据是否发生下肢血管病变将其分成两组,比较两组患者临床各项指标,探讨2型糖尿病发生下肢血管病变的危险因素。结果65例患者出现下肢血管病变,发生率为33.16%;其中下肢血管病变组患者年龄、病程、收缩压(SBP)、糖化血红蛋白(HbA1c)以及餐后2 h血糖(P2BG)水平均高于未下肢血管病变组,比较差异具有统计学意义(P<0.05),其他如性别、舒张压(DBP)、心率水平(HR)、体质量指数(BMI)、空腹血糖(FBG)、总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL)、低密度脂蛋白胆固醇(LDL)等各项指标差异无统计学意义(P>0.05)。多因素Logistic回归分析显示,年龄、病程、SBP、HbA1c以及P2BG是2型糖尿病下肢血管病变的独立影响因素(P<0.05),年龄越大、病程越长,收缩压越高,HbA1c和P2BG越高,下肢血管病变的发生可能性更大。结论2型糖尿病下肢血管病变发生率较高,其危险因素包括患者年龄、病程、SBP、HbA1c以及餐后2 h血糖水平,因而在临床工作中需注意结合患者的年龄和病程,指导患者加强患者血糖及血压水平的控制和调理,以控制下肢血管病变发生风险。
Objective To analyze the incidence of lower extremity vascular disease in type 2 diabetes mellitus and to summarize its risk factors.Methods Totally 196 patients with type 2 diabetes mellitus(n=196)admitted to Tongzhou Bay Sanyu People's Hospital from January 2018 to January 2020 were selected as the research objects.Ultrasound examination was performed on all patients to summarize the incidence of vascular disease of lower limbs.The patients were divided into two groups according to the occurrence of lower extremity vascular disease.The clinical indexes of the two groups were compared,and the risk factors of lower extremity vascular disease in type 2 diabetes mellitus were analyzed.Results 65 patients with lower extremity vascular disease,the incidence rate was 33.16%;the age,course of disease,SBP,HbA1c and 2 h postprandial blood glucose levels in patients with lower extremity vascular disease group were higher than those in non lower limb vascular disease group,the difference was statistically significant(P<0.05),there were no significant differences in gender,DBP,heart rate,BMI,fasting blood glucose,TC,TG,HDL,LDL,etc(P>0.05).Multivariate Logistic regression showed that age,course of disease,SBP,HbA1c and postprandial 2 h blood glucose were independent risk factors(P<0.05).The older the age,the longer the course of disease,the higher the blood pressure,the higher the HbA1c and postprandial 2 h blood glucose,the higher the possibility of vascular disease of lower limbs.Conclusion The incidence of lower extremity vascular disease in type 2 diabetes mellitus is high,and the risk factors include patient's age,course of disease,SBP,HbA1c and 2 h postprandial blood glucose level.In clinical work,it is necessary to guide patients to strengthen the control and conditioning of blood glucose and blood pressure level in order to control the risk of lower extremity vascular disease.
作者
孙甦
张菊红
江开颜
SUN Su;ZHANG Juhong;JIANG Kaiyan(Tongzhou Bay Sanyu People's Hospital,Nantong,Jiangsu 226331,China)
出处
《大医生》
2020年第20期4-6,共3页
Doctor
关键词
2型糖尿病
下肢血管病变
发生率
危险因素
type 2 diabetes mellitus
lower extremity vascular disease
incidence
risk factors
