摘要
【目的】观察温针灸治疗脾肾阳虚型亚临床甲状腺功能减退症患者的临床疗效。【方法】将56例脾肾阳虚型亚临床甲状腺功能减退症患者随机分为治疗组30例和对照组26例。对照组给予生活调摄方面的指导,并无药物或针灸治疗。治疗组在对照组治疗的基础上,给予温针灸治疗,2组均治疗8周。治疗8周后,观察2组患者治疗前后血清游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺素(TSH)含量及抗甲状腺过氧化物酶抗体(TPOAb)的变化情况,以及2组患者治疗前后中医症状积分和主要临床症状积分的变化情况。【结果】(1)治疗后,治疗组患者的TSH水平明显改善,与同组治疗前比较,差异有统计学意义(P<0.05),对照组患者的TSH水平虽有改善,但与同组治疗前比较,差异无统计学意义(P>0.05);治疗组在改善TSH水平方面明显优于对照组,差异有统计学意义(P<0.05)。治疗后,2组患者的FT3、FT4水平均明显升高,但与治疗前比较,差异无统计学意义(P>0.05);2组间比较,差异亦无统计学意义(P>0.05)。(2)治疗后,对照组患者的TPOAb水平与治疗前比较,差异无统计学意义(P>0.05),治疗组患者的TPOAb水平明显改善(P<0.05),且治疗组在改善TPOAb水平方面明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,治疗组患者的症状总积分明显改善(P<0.05),且治疗组在改善症状总积分方面明显优于对照组,差异有统计学意义(P<0.05)。(4)治疗后,治疗组患者的各项主要症状积分均明显改善(P<0.05),且治疗组在改善各项主要症状积分方面明显优于对照组,差异有统计学意义(P<0.05)。(5)治疗组总有效率为86.67%(26/30),对照组为0%(0/26)。治疗组疗效优于对照组,差异有统计学意义(P<0.05)。【结论】温针灸治疗脾肾阳虚型亚临床甲状腺功能减退症,可明显降低患者TSH、TPOAb水平,改善患者的临床症状,提高患者的生活质量,疗效显著
Objective To observe the therapeutic effect of moxibustion with warming needle for spleen-kidney yang deficiency type of subclinical hypothyroidism. Methods Fifty-six patients with spleen-kidney yang deficiency type of subclinical hypothyroidism were randomly divided into treatment group(30 cases)and control group(26 cases).The control group received guiding health nursing, and no medication or acupuncture-moxibustion treatment,additionally,the treatment group received moxibustion with warming needle on the basis of the treatment of the control group,the treatment lasting 8 weeks in the two groups. After 8-week treatment,the changes in levels of serum free triiodinated thyrotropine(FT3),free thyroxine(FT4),thyroid stimulating hormone(TSH)and thyroid peroxidase antibody(TPOAb)were observed in the two groups before and after treatment, and the traditional Chinese medicine(TCM)symptoms scores and main clinical symptoms scores in the two groups before and after treatment were compared. Results(1)After treatment,the TSH level in the treatment group was improved,the difference being significant as compared to that in the same group before treatment(P<0.05),TSH level in the control group was improved, the difference being insignificant as compared to that in the same group before treatment(P>0.05),and the improvement in TSH level of the treatment group was superior to that of the control group,the differences being significant(P<0.05). After treatment,the FT3 and FT4 levels in the two groups were increased,but the differences were insignificant as compared to that before treatment(P>0.05),and the differences were also insignificant between the two groups(P>0.05).(2)After treatment,the difference in TPOAb level in the control group was insignificant as compared to that before treatment(P>0.05),TPOAb level in the treatment group was improved(P<0.05), and the improvement in TPOAb level of the treatment group was superior to that of the control group, the difference being significant(P<0.05).(3)After treatment, the total sc
作者
张静毅
邹萍
方庆霞
ZHANG Jing-Yi;ZOU Ping;FANG Qing-Xia(Beijing Second Hospital,Beijing 100031,China;Dept.of Gynecology,Xiyuan Hospital of China Academy of Chinese Medical Science,Beijing 100091)
出处
《广州中医药大学学报》
CAS
2021年第2期294-300,共7页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
北京中医药薪火传承“3+3”工程项目(编号:2009-JC-01)
北京市西城区2016年度青年科技人才项目(编号:XWKX2016-02)。
关键词
温针灸
脾肾阳虚
亚临床甲状腺功能减退
促甲状腺素
抗甲状腺过氧化物酶抗体
临床观察
moxibustion with warming needle
spleen-kidney yang deficiency
subclinical hypothyroidism
clinical observation
thyroid stimulating hormone(TSH)
thyroid peroxidase antibody(TPOAb)
