摘要
【目的】采用关节超声评价固本通痹药罐与清水罐治疗类风湿关节炎的临床疗效。【方法】将123例类风湿关节炎患者随机分为观察组(固本通痹药罐组)62例和对照组(清水罐组)61例。2组患者均给予常规中西医结合治疗和护理,在此基础上,观察组给予固本通痹药罐疗法(取足三里、血海、阳陵泉、阴陵泉、膝阳关等穴位)治疗,对照组给予清水罐疗法治疗,疗程为7 d。以关节超声下的2组患者治疗前后关节滑膜增生度、关节滑膜血流、关节腔积液的变化情况作为主要结局指标,并以2组患者治疗前后血沉(ESR)、C反应蛋白(CRP)的变化情况作为次要结局指标,评价2组患者的临床疗效。【结果】(1)治疗后,观察组患者的膝关节滑膜血流和关节腔积液较对照组明显减少(P <0.01),而2组患者的膝关节滑膜增生改善不明显,差异无统计学意义(P> 0.05)。(2)治疗后,2组患者的ESR、CRP水平均较治疗前明显降低(P <0.01),且观察组对CRP水平的降低作用明显优于对照组,差异有统计学意义(P <0.05)。【结论】固本通痹药罐能有效减少关节滑膜血流、促进关节腔积液吸收,具有可操作性强、安全性好、疗效显著、副作用少等优点;关节超声检查能有效评价临床治疗效果,提供客观的评价依据,可作为一种良好的检测手段辅助进行治疗效果的评价。
Objective To evaluate the curative effect of Guben Tongbi medicated cup and water cup for the treatment of rheumatoid arthritis based on joint ultrasound examination. Methods A total of 123 rheumatoid arthritis patients were randomly divided into the observation group(62 cases)and the control group(61 cases). All patients in both groups were given basic Chinese and western medicine treatment and routine nursing for rheumatoid arthritis. And additionally,the observation group was given Guben Tongbi medicated cupping therapy on the points of Zusanli(ST36),Xuehai(SP10),Yanglingquan(GB34),Yinlingquan(SP9),and Xiyangguan(GB33)for consolidating vital base and relieving obstruction,and the control group was given water cupping therapy on the same points. The treatment for the two groups lasted for 7 days. Before and after treatment, we observed the changes in the primary outcomes of joint synovial hyperplasia,joint synovial blood flow,and articular effusion with joint ultrasound examination,and detected the secondary outcomes of erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)in the two groups, so as to evaluate the clinical efficacy. Results(1)After treatment,joint synovial blood flow and articular effusion in the observation group were decreased in comparison with those in the control group(P < 0.01),but the improvement of joint synovial hyperplasia in the two groups was not obvious in comparison with that before treatment(P > 0.05).(2)After treatment,ESR and CRP levels in the two groups were obviously decreased(P < 0.01),and the observation group had stronger effect on decreasing CRP than the control group, the difference being statistically significant(P < 0.05). Conclusion Guben Tongbi medicated cupping therapy can effectively reduce the synovial blood flow and promote the absorption of articular effusion. The therapy has the advantages of good operability and safety,significant curative effect,and few side effects. Joint ultrasound can effectively evaluate the clinical therapeutic effect,and can prov
作者
杨湘薇
张明英
蔡超英
胡艺译
冼贞
杨梅
YANG Xiang-Wei;ZHANG Ming-Ying;CAI Chao-Ying;HU Yi-Yi;XIAN Zhen;YANG Mei(The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405 Guangdong,China;The Yuexiu Meihua Community Health Service Center,Guangzhou 510062 Guangdong,China)
出处
《广州中医药大学学报》
CAS
2021年第2期278-283,共6页
Journal of Guangzhou University of Traditional Chinese Medicine
基金
国家中医药管理局“十二五”风湿病科重点专科建设项目
广州中医药大学第一附属医院“创新强院”工程系列科研项目(编号:2015HL03)。
关键词
药物罐
固本通痹法
关节超声
类风湿关节炎
medicated cup
Guben Tongbi therapy(therapy for consolidating vital base and relieving obstruction)
joint ultrasound
rheumatoid arthritis
