摘要
综述了温度对生命体寿命的作用,包括温度参与调节特定基因表达和细胞信号传导通路,温度对能量代谢、氧化还原水平、免疫功能和热量限制的影响。介绍了一种将温度系数引入死亡率定律的假设,以此计算温度与寿命之间的关系,为探究温度对寿命的直接影响提供参考和依据。
The effects of temperature on the lifespan of living organisms were reviewed,including the temperature regulating specific gene expression and cell signaling pathways,as well as the effects of temperature on energy metabolism,redox levels,immune function,and caloric restriction.A hypothesis of introducing a temperature coefficient into the law of mortality was presented to calculate the relationship between temperature and lifespan,which provides a reference and basis for exploring the direct influence of temperature on lifespan.
作者
赵佐舜
刘宝林
ZHAO Zuoshun;LIU Baolin(School of Medical Instrument and Food Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China)
出处
《上海理工大学学报》
CAS
CSCD
北大核心
2020年第6期543-549,共7页
Journal of University of Shanghai For Science and Technology
关键词
温度
衰老
延长寿命
基因表达
生化反应
temperature
aging
life-extension
gene expression
biochemical reaction
