摘要
目的观察朱琏针法对多囊卵巢综合征(PCOS)伴睡眠障碍患者睡眠质量及性激素水平的影响,探讨朱琏针法改善睡眠障碍PCOS患者的作用机理。方法将60例伴有睡眠障碍的PCOS患者随机分为对照组和朱琏组,每组30例,对照组给予达英-35治疗,朱琏组在朱琏针法治疗PCOS的针灸选穴基础上配伍神门穴施治,两组均给予常规PCOS宣教及睡眠指导,疗程均为3个月经周期,对比治疗前后两组患者匹兹堡睡眠质量指数(PSQI)及性激素六项变化的差异。结果两组PCOS患者的PSQI与治疗前相比均显著下降(P<0.05或0.01),朱琏组治疗后对睡眠障碍的改善情况优于对照组(P<0.05),其中朱琏组在睡眠质量、入睡时间、睡眠障碍及日间功能障碍指数均低于对照组(P<0.05或0.01)。两组患者治疗后黄体生成激素(LH)水平均较治疗前显著下降(P<0.05),对照组睾酮(T)水平较治疗前显著下降(P<0.05),两组治疗后激素六项水平比较差异均无统计学意义(P>0.05)。结论朱琏针法能显著改善PCOS患者的睡眠质量,并具有一定的激素调节作用,值得深入研究。
Objective To observe the effect of ZHU Lian's acupuncture on sleep quality and sex hormone levels in polycystic ovary syndrome(PCOS)patients with sleep disorder,and to explore the mechanism of ZHU Lian's acupuncture in improving sleep disorders of PCOS patients.Methods 60 PCOS patients with sleep disorders were randomly divided into control group and ZHU Lian's group,with 30 cases in each group.The control group were treated by Daine-35,and the ZHU Lian's group were given treatment on Shenmen acupoint on the basis of acupoint selection of PCOS treated by ZHU Lian's acupuncture.Both groups were given routine PCOS education and sleep instruction,and the course of treatment was 3 menstrual cycles.And then,Pittsburgh Sleep Quality Index(PSQI)and six sexual hormones were tested before and after the treatment.Results The PSQI of PCOS in both groups decreased significantly compared with those before treatment(P<0.05 or 0.01),and the improvement of sleep disorder in the ZHU Lian's group was better than that in the control group(P<0.05),and the sleep quality,sleep time,sleep disorder and daytime dysfunction index in the ZHU Lian's group were lower than those in the control group(P<0.05 or 0.01).After treatment,luteinizing hormone(LH)levels of the two groups decreased significantly(P<0.05),and testosterone(T)level of the control group decreased remarkably(P<0.05).However,there was no statistically significant difference in six hormone levels between the two groups after treatment(P>0.05).Conclusion ZHU Lian's acupuncture can significantly improve the sleep quality of PCOS patients,and has a certain hormone regulatory effect,which is worthy of further study.
作者
岳进
陈敏
易蕾
刘春芬
苏小莉
方誉
YUE Jin;CHEN Min;YI Lei;LIU Chunfen;SU Xiaoli;FANG Yu(Department of Preventive Treatment of Diseases,Nanning Hospital of Traditional Chinese Medicine,Nanning 530012,Guangxi,China;Department of Gynaecology,Xinhua Branch of Nanning Hospital of Traditional Chinese Medicine,Nanning 530012,Guangxi,China;Department of Science and Education,Nanning Hospital of Traditional Chinese Medicine,Nanning 530001,Guangxi,China)
出处
《右江医学》
2020年第12期915-919,共5页
Chinese Youjiang Medical Journal
基金
广西科技计划项目(桂科AB16380209)。
