摘要
Spontaneous esophageal rupture,or Boerhaave syndrome,is a rare but potentially fatal condition with a mortality rate ranging from 20%to 30%in the literature.[1]In some European countries,the incidence is below 3 to 6/1,000,000 persons.[2]Nowadays,the treatment of this disease remains a challenge to physicians due to the variable clinical manifestations and lack of consensus or guidelines.[3]To better understand this disease and summarize our experience in this field,we searched the medical files at our hospital using both electronic and manual methods.Herein,we report a series of 73 patients with spontaneous esophageal rupture in a single center over two decades.Between April 1983 and June 2013,a total of 73 consecutive patients were diagnosed with spontaneous esophageal rupture at the Fourth Hospital of Hebei Medical University.The clinical data were collected retrospectively with all of the patients’informed consent and the study was conducted in accordance with the Declaration of Helsinki.