摘要
目的研究益气活血方对冠心病患者介入支架植入术后患者的疗效及发作频率、疼痛持续时间的变化影响。方法选取医院2015年12月—2018年12月经皮冠状动脉支架植入(PCI)的冠心病患者86例,根据治疗方法不同分为两组。对照组给予常规西药治疗,观察组给予常规西药治疗联合益气活血方治疗,分析两组患者治疗后的临床疗效。结果两组治疗前心绞痛每周发作频率、每次疼痛持续时间水平组间比较,差异不具有统计学意义(P>0.05)。观察组治疗后心绞痛每周发作频率(4.75±0.58)次低于对照组(6.04±0.67)次,每次疼痛持续时间[(2.74±0.78)min]短于对照组[(3.65±0.86)min],差异具有统计学意义(P<0.05)。观察组总有效率为90.70%(39/43),对照组为74.42%(32/43),观察组患者总有效率高于对照组(P<0.05)。两组治疗前血清亲环素A(CyPA)、C反应蛋白(CRP)、血清妊娠相关蛋白-A(PAPP-A)水平组间比较,差异不具有统计学意义(P>0.05)。观察组治疗后CyPA、CRP、PAPP-A水平低于对照组(P<0.05)。两组治疗前生活质量评分组间比较,差异不具有统计学意义(P>0.05)。观察组治疗后生活质量各项评分低于对照组(P<0.05)。结论益气活血方用于冠心病介入术后可减少心绞痛发作频率,降低CyPA、CRP、PAPP-A的表达水平,提高生活质量。
Objective To study the effect of Yiqi Huoxue Recipe on the clinical efficacy, frequency of onset and duration of pain in patients with coronary heart disease(CHD) after stent implantation. Methods From December 2015 to December 2018, 86 patients with coronary heart disease underwent percutaneous coronary stent implantation(PCI) were divided into two groups according to different treatment methods. The control group was treated with conventional western medicine, and the observation group was treated with routine western medicine combined with Yiqi Huoxue Recipe. The clinical curative effects of the two groups were analyzed. Results There was no significant difference in the frequency of angina pectoris and the duration of each pain between the two groups before treatment(P>0.05). After treatment, the frequency of angina pectoris[(4.75 ±0.58) times per week] in the observation group was lower than that in the control group [(6.04 ±0.67) times per week], and the duration of each pain[(2.74±0.78) min] was shorter than that in the control group[(3.65±0.86)min]. The difference was statistically significant(P<0.05). The total effective rate was 90.70% in the observation group and 74.42% in the control group, and the total effective rate in the observation group was higher than that in the control group(P<0.01). There was no significant difference in the levels of serum A(CyPA) or C-reactive protein-A(PAPP-A) between two groups before treatment(P>0.05), but there was no significant difference between the two groups in the levels of serum pregnancy-associated protein-A(PAPP-A) before treatment. After treatment, the levels of CyPA,CRP and PAPP-A in the observation group were lower than those in the control group(P<0.05), and there was no significant difference in the quality of life score between the two groups before treatment(P>0.05). The scores of quality of life in the observation group after treatment were lower than those in the control group(P<0.05). Conclusion Yiqi Huoxue Recipe can reduce the frequency of ang
作者
张红艳
朱晓菡
史云菊
韩芬
ZHANG Hongyan;ZHU Xiaohan;SHI Yunju;HAN Fen(Zhengzhou Railway Vocational and Technical College,Zhengzhou 451460,Henan,China)
出处
《中华中医药学刊》
CAS
北大核心
2020年第12期45-48,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家卫生计生委医药卫生科技发展计划(W2017JZC63)
河南省科技发展计划软科学研究基金(172400410372)。
关键词
益气活血方
冠心病
支架植入
疗效
生活质量
Yiqi Huoxue Recipe
coronary heart disease
stent implantation
curative effect
quality of life
