摘要
肿瘤患者发生睡眠障碍的危险因素包括肿瘤、治疗因素、药物、环境因素、心理障碍和共患病等[1]。肿瘤可以导致多巴胺、γ-氨基丁酸、去甲肾上腺素、肾上腺素、5-羟色胺、组胺等神经递质与内分泌激素水平紊乱,影响睡眠觉醒中枢,导致睡眠障碍。睡眠障碍也通过影响免疫功能导致肿瘤的进展。
The risk factors of sleep disorders in cancer patients include tumor,treatment,drugs,environmental,psychological disorders and comorbidities.Tumors can lead to disorders of neurotransmitters and endocrine hormones,such as dopamine,GABA,norepinephrine,epinephrine,5-hydroxytryptamine,histamine,etc.,and affect the sleep wake center,leading to sleep disorders.Sleep disorders also contribute to tumor progression by affecting immune function.
作者
于洁洋
郭笑
王亚茹
李惠敏
王赞
YU Jieyang;GUO Xiao;WANG Yaru;LI Huimin;WANG Zan(The First Hospital of Jilin University,Neurology Department,Jilin 130021,China)
出处
《世界睡眠医学杂志》
2020年第11期2041-2044,共4页
World Journal of Sleep Medicine
关键词
肿瘤
睡眠障碍
免疫功能
Tumor
Sleep Disorder
Immune function
