摘要
目的:观察高频rTMS对PD患者肢体运动能力及睡眠状况的影响。方法:40例PD患者均分为2组,每组20例,观察组采取高频rTMS治疗,对照组接受伪刺激治疗,同时保持2组原有药物治疗方案不变,记录并比较2组PD患者在治疗前、后统一帕金森评定量表(UPDRSⅢ)、帕金森病睡眠量表(PDSS)及帕金森病生命质量问卷(PDQ-39)的分值变化。结果:治疗后2组UPDRSⅢ、PDSS及PDQ-39评分均有明显差别,PD患者肢体运动能力、睡眠状况及生命质量均较治疗前改善,且观察组优于对照组(P<0.05)。结论:高频rTMS治疗PD疗效肯定,对肢体运动能力、睡眠状况及生命质量均有积极的影响。
Objective:To observe the effect of high-frequency rTMS on limb movement ability and sleep status of PD patients.Methods:A total of 40 patients with PD were divided into two groups,20 cases in each group.The study group was treated with high frequency rTMS,while the control group was treated with pseudo stimulation.At the same time,the original drug treatment plan of the two groups remained unchanged.The scores of UPDRSⅢ,PDSS and PDQ-39 were recorded and compared between the two groups before and after treatment.Results:After treatment,the scores of UPDRSⅢ,PDSS and PDQ-39 were significantly different between the two groups.Limb motor ability,sleep status and quality of life of PD patients were improved compared with those before treatment,and the study group was better than the control group(P<0.05).Conclusion:High-frequency rTMS is effective in the treatment of PD,and it has a positive effect on limb motor ability,sleep status and quality of life.
作者
赖靖慧
蔡扬帆
夏敏
邱丽芳
翁婧
杨丽艳
张仁雄
LAI Jinghui;CAI Yangfan;XIA Min;QIU Lifang;WEN Jing;YANG Liyan;ZHANG Renxiong(Rehabilitation Hospital affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350003,China;Fujian Key Laboratory of Rehabilitation Technology,Fuzhou 350003,China)
出处
《世界睡眠医学杂志》
2020年第11期1861-1863,共3页
World Journal of Sleep Medicine
基金
中央引导地方科技发展专项(2018L3009)。
关键词
经颅重复磁刺激
辅助运动区
帕金森病
运动功能
睡眠
Transcranial repetitive magnetic stimulation
Auxiliary motor area
Parkinson′s disease
Motor function
Sleep
