摘要
目的:观察中药浸泡联合盐酸帕罗西汀治疗早泄的临床疗效。方法:将120例早泄患者随机分为治疗组和对照组各60例。对照组口服盐酸帕罗西汀,20 mg/次,1次/d,午餐后顿服。治疗组在对照组的基础上采用中药浸泡,将阴茎头置于100 mL中药煎剂中(35~40℃),浸泡15~20 min,1次/d。两组均连续治疗4周。治疗前后记录患者阴道内射精潜伏时间(IELT)、早泄简表(PEP)评分,比较两组有效率。结果:至试验结束,共有107例患者完成观察,治疗组55例,对照组52例。两组患者治疗后IELT及PEP评分均提高,差异均有统计学意义(P<0.01),且治疗组患者治疗后IELT及PEP评分明显高于对照组(P<0.01)。治疗组和对照组总有效率分别为87.27%(48/55)和71.15%(37/52),治疗组优于对照组,差异有统计学意义(P<0.05)。结论:中药浸泡联合盐酸帕罗西汀治疗早泄可明显提高早泄患者IELT、PEP,且疗效优于单用盐酸帕罗西汀。
Objective: To observe the clinical effect of traditional Chinese medicine soaking combined with paroxetine hydrochloride in the treatment of premature ejaculation. Methods: 120 patients with premature ejaculation were randomly divided into treatment group 60 cases and control group 60 cases. The control group received paroxetine hydrochloride, 20 mg/time, once a day, and then took it after lunch. The treatment group was immersed in traditional Chinese medicine on the basis of the control group. The specific method was as follows:the penis head was placed in 100 mL of Chinese medicine decoction at about 35-40 ℃, and soaked for about15 to 20 minutes, once a day. Both groups were treated continuously for 4 weeks. Before and after treatment,the patient’s intravaginal ejaculation latency time(IELT) and the premature ejaculation profile(PEP) scores were recorded and compared between groups to compare the effectiveness of the two groups. Results: By the end of the trial, a total of 107 patients had completed the observation, with 55 in the treatment group and 52 in the control group. After treatment, the IELT and PEP scores of the two groups were increased, and the differences were statistically significant(P<0.01). The IELT and PEP scores of the treatment group were significantly higher than those of the control group(P<0.01). The total effective rates of the treatment group and the control group were 87.27%(48/55) and 71.15%(37/52), respectively. The treatment group was better than the control group,and the difference was statistically significant(P<0.05). Conclusion: The traditional Chinese medicine soaking combined with paroxetine hydrochloride for premature ejaculation can significantly improve IELT and PEP in patients with premature ejaculation, and the effect is better than paroxetine hydrochloride alone.
作者
刘建国
赵红乐
赵宇涛
马亚玲
李姣姣
LIU Jian-guo;ZHAO Hong-le;ZHAO Yu-tao;MA Ya-ling;LI Jiao-jiao(Shaanxi Province Hospital of Traditional Chinese Medicine,Xi'an Shaanxi 710003,China;Shaanxi University of Chinese Medicine,Xianyang Shaanxi 712046,China)
出处
《中医药导报》
2020年第16期81-84,共4页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金项目(81603631)
陕西省自然基金项目(2016JQ8034)。
关键词
早泄
中药浸泡
盐酸帕罗西汀
射精潜伏时间
premature ejaculation
traditional Chinese medicine soaking
paroxetine
intravaginal ejaculation latency time
