摘要
目的探讨慢性阻塞性肺疾病合并外周血管病的危险因素。方法回顾性分析2016年12月~2019年12月沈阳市第一人民医院收治的80例慢性阻塞性肺疾病接受外周血管疾病相关检查患者的临床资料,诊断存在明确外周血管疾病患者40例为发病组,排除外周血管疾病患者40例为未发病组。分析性别、年龄、存在吸烟史、存在饮酒史、合并高血压、合并肺源性心脏病、合并2型糖尿病、合并高脂血症及合并冠心病对慢性阻塞性肺疾病合并外周血管疾病发病的影响。结果单因素分析结果显示,两组的吸烟史、饮酒史、合并高血压、合并肺源性心脏病、合并2型糖尿病、合并高脂血症及合并冠心病比较,差异有统计学意义(P<0.05)。多因素分析结果提示,存在吸烟史(β=2.349,OR=2.819,95%CI=1.219~3.408)、合并高血压(β=1.833,OR=5.167,95%CI=1.035~5.457)、合并肺源性心脏病(β=2.925,OR=5.868,95%CI=1.596~6.245)、合并2型糖尿病(β=1.712,OR=5.523,95%CI=2.102~7.836)及合并高脂血症(β=1.293,OR=2.446,95%CI=1.381~4.319)为慢性阻塞性肺疾病合并外周血管疾病发病的独立危险因素(P<0.05)。慢性阻塞性肺疾病合并外周血管疾病患病率与吸烟史时间、合并2型糖尿病病程、合并高血压病程、合并高脂血症病程、合并肺炎性心脏病病程和合并冠心病病程等呈正相关(P<0.05)。结论吸烟史、高血压、肺源性心脏病、2型糖尿病、高脂血症为慢性阻塞性肺疾病合并外周血管疾病发病的相关及独立危险因素,且其病程与慢性阻塞性肺疾病合并外周血管疾病患病率呈正相关。
Objective To explore the risk factors of chronic obstructive pulmonary disease complicated with peripheral vascular disease.Methods A retrospective analysis was carried out on 80 patients with chronic obstructive pulmonary disease in Shenyang First People′s Hospital who received peripheral vascular disease-related examinations from December 2016 to December 2019 were choosed.40 patients diagnosed with definite peripheral vascular disease were the onset group,and 40 patients excluded from peripheral vascular disease were the non-onset group.The influence of gender,age,smoking history,drinking history,hypertension,pulmonary heart disease,type 2 diabetes,hyperlipidemia and coronary heart disease on the incidence of chronic obstructive pulmonary disease combined with peripheral vascular diseases were analysed.Results The results of single factor analysis showed that there were significant differences in smoking history,drinking history,hypertension,pulmonary heart disease,type 2 diabetes,hyperlipidemia and coronary heart disease(P<0.05).Multivariate analysis showed that smoking history(β=2.349,OR=2.819,95%CI=1.219-3.408),hypertension(β=1.833,OR=5.167,95%CI=1.035-5.457),pulmonary heart disease(β=2.925,OR=5.868,95%CI=1.596-6.245),type 2 diabetes mellitus(β=1.712,OR=5.523,95%CI=2.102-7.836)and hyperlipidemia(β=1.293,OR=2.446,95%CI=1.381-4.319)were independent risk factors for the onset of chronic obstructive pulmonary disease combined with peripheral vascular disease(P<0.05).Course of disease complicated with type 2 diabetes,course of disease complicated with hypertension,course of disease complicated with hyperlipidemia,course of disease complicated with pneumonia heart disease and course of disease complicated with coronary heart disease were positively correlated with the prevalence rate of chronic obstructive pulmonary disease combined with peripheral vascular disease(P<0.05).Conclusion Smoking history,hypertension,pulmonary heart disease,type 2 diabetes,hyperlipidemia and coronary heart disease are the relev
作者
杜树微
DU Shu-wei(Department of Respiratory Medicine,Shenyang First People′s Hospital,Liaoning Province,Shenyang110041,China)
出处
《中国当代医药》
2020年第36期70-73,共4页
China Modern Medicine
关键词
慢性阻塞性肺疾病
外周血管病
相关危险因素
独立危险因素
Chronic obstructive pulmonary disease
Peripheral vascular disease
Relevant risk factors
Independent risk factors
