摘要
目的探究胱抑素C、尿微量白蛋白/肌酐比值运用在早期糖尿病肾病诊断中的有效性。方法挑选2017年3月—2019年3月在医院进行治疗的糖尿病患者116例记作研究组,按照数字表法平分为肾病组与非肾病组,每组58例。随机纳入同期在医院进行健康体检人员58名记作基础组。分别收集医学分析对象自身的血清和尿液,比较研究对象胱抑素C、尿微量白蛋白/肌酐比值,了解胱抑素C、尿微量白蛋白/肌酐比值对早期糖尿病肾病诊断价值。结果在统计与记录之后,肾病组患者胱抑素C(1.40±0.62)mg/L、尿微量白蛋白/肌酐比值(7.05±4.12)mg/mmol、血糖(6.32±1.24)mmol/L;非肾病组患者胱抑素C (0.77±0.21)mg/L、尿微量白蛋白/肌酐比值(1.94±1.20)mg/mmol、血糖(6.50±2.08)mmol/L;基础组患者胱抑素C(0.70±0.14)mg/L、尿微量白蛋白/肌酐比值(1.57±1.01)mg/mmol、血糖(5.20±0.32)mmol/L;基础组人员和非肾病组患者体内的胱抑素C、尿微量白蛋白/肌酐比值差异无统计学意义(P>0.05)。基础组血糖均小于肾病组与非肾病组(P<0.05),而肾病组患者与非肾病组患者血糖对比差异无统计学意义(P>0.05)。肾病组患者体内的胱抑素C、尿微量白蛋白/肌酐比值较基础组患者较非肾病组患者数值大,差异有统计学意义(P<0.05)。结论早期糖尿病肾病诊断中胱抑素C、尿微量白蛋白/肌酐比值的临床研究存在较强意义和价值,医学上可以通过胱抑素C、尿微量白蛋白/肌酐比值对早期糖尿病肾病进行诊断,提高医学诊断率。
Objective To explore the effectiveness of cystatin C and urine microalbumin/creatinine ratio in the early diagnosis of diabetic nephropathy.Methods A total of 116 diabetic patients who were treated in the hospital from March 2017 to March 2019 were selected as the study group,and the nephropathy group and the non-nephropathy group were scored according to the number table.The number of personnel in each group was 58 cases.58 health checkups in the hospital during the same period were randomly included as the routine group.Collected the serum and urine of the medical analysis subjects,compared the cystatin C,urine microalbumin/creatinine ratio of these people,and understood the value of cystatin C and urine microalbumin/creatinine ratio for the diagnosis of early diabetic nephropathy.Results After statistics and records,cystatin C(1.40±0.62)mg/L,urinary microalbumin/creatinine ratio(7.05±4.12)mg/mmol,blood sugar(6.32±1.24)mmol/L in nephropathy group;non-nephropathy Cystatin C(0.77±0.21)mg/L,urinary microalbumin/creatinine ratio(1.94±1.20)mg/mmol,blood glucose(6.50±2.08)mmol/L in the basic group;Cystatin C(0.70±0.14)mg/L,urine microalbumin/creatinine ratio(1.57±1.01)mg/mmol,blood sugar(5.20±0.32)mmol/L.There was not statistically significant difference in cystatin C and urine microalbumin/creatinine ratio between the basic group and the non-nephropathy group(P>0.05).The blood glucose of the basic group was lower than that of the nephropathy group and the non-nephropathy group,and the difference was statistically significant(P<0.05),but there was not statistically significant difference in blood glucose between the nephropathy group and the non-nephropathy group(P>0.05).Cystatin C and urine microalbumin/creatinine ratio in the nephropathy group were higher than those in the basic group and non-nephropathy,the group value was large,and the difference was statistically significant(P<0.05).Conclusion The clinical research of cystatin C and urine microalbumin/creatinine ratio in the diagnosis of early diabetic
作者
张晓洁
连云宗
ZHANG Xiao-jie;LIAN Yun-zong(Department of Laboratory Medicine,Quanzhou First Hospital,Fujian Medical University,Quanzhou,Fujian Province,362000 China)
出处
《糖尿病新世界》
2020年第22期37-39,共3页
Diabetes New World Magazine
