摘要
目的:探讨血清降钙素原在鉴别急性肾盂肾炎和下尿路感染中的诊断价值。方法:2016年2月-2018年2月收治尿路感染患者47例,根据感染部位分为急性肾盂肾炎组21例和下尿路感染组26例,比较两组患者血清C反应蛋白(CRP)、白细胞计数(WBC)和降钙素原(PCT)水平。再根据急性肾盂肾炎有无合并梗阻分为两组,比较两组PCT水平。结果:急性肾盂肾炎组CRP、WBC和PCT水平均高于下尿路感染组,差异有统计学意义(P<0.01)。PCT在诊断急性肾盂肾炎时的灵敏度为85.3%,特异度为80.1%。急性肾盂肾炎合并梗阻患者血清PCT水平高于急性肾盂肾炎无梗阻患者,差异有统计学意义(P<0.01)。结论:CRP、WBC和PCT均可以用作区分急性肾盂肾炎和下尿路感染的有效指标,但PCT在预测急性肾盂肾炎时有更好的灵敏度和特异度。PCT水平在急性肾盂肾炎合并梗阻中较无梗阻显著升高。
Objective:To investigate the diagnostic value of serum procalcitonin in the differential diagnosis of acute pyelonephritis and lower urinary tract infection.Methods:From February 2016 to February 2018,47 patients with urinary tract infection were selected and divided into acute pyelonephritis group(21 cases)and lower urinary tract infection group(26 cases)according to the infection site,serum CRP,WBC and PCT levels were compared between the two groups.According to the presence or absence of obstruction in acute pyelonephritis,they were divided into two groups,PCT levels were compared between the two groups.Results:In acute pyelonephritis group,CRP,WBC and PCT levels were significantly higher than those in lower urinary tract infection group,the difference was statistically significant(P<0.01).The sensitivity of PCT in the diagnosis of acute pyelonephritis was 85.3%,the specificity was 80.1%.The serum PCT level in patients with acute pyelonephritis and obstruction was higher than that in patients without obstruction,the difference was statistically significant(P<0.01).Conclusion:CRP,WBC and PCT can be used as effective indicators to distinguish acute pyelonephritis from lower urinary tract infection,however,PCT has better sensitivity and specificity in predicting acute pyelonephritis.PCT level in acute pyelonephritis with obstruction is significantly higher than that without obstruction.
作者
蔡斌
Cai Bin(Department of Nephrology and Endocrinology,the People's Hospital of Daye City,Hubei Daye 435100)
出处
《中国社区医师》
2021年第1期83-84,共2页
Chinese Community Doctors
关键词
降钙素原
C反应蛋白
急性肾盂肾炎
Procalcitonin
C-reactive protein
Acute pyelonephritis
