摘要
目的分析药物联合正念认知疗法对抑郁症患者康复获益的影响。方法将2019年7月-2020年7月在本院心身医学科接受治疗的抑郁症70例患者随机分为干预组(36例)和对照组(34例),干预组给予盐酸文拉法辛联合正念认知疗法,对照组仅予盐酸文拉法辛治疗,于住院前和出院时用汉密尔顿抑郁量表(HAMD--24)、症状自评量表(SCL-90)和社会功能缺陷量表(SDSS)进行评定,比较两组患者抑郁症状及社会功能改善情况,并对两组患者治愈率及平均住院时间做对照分析。结果①平均住院时间干预组为24.78±2.45天,对照组为29.02±2.24天,干预组明显少于对照组,差异具有统计学意义(P<0.01)。②出院时治愈率干预组为75.0%,对照组为55.%,干预组高于对照组,但差异无统计学意义(P>0.05)。③HAMD-24、SDSS、SCL-90评分干预前干预组和对照组差异无统计学意义(P>0.05);干预后HAMD-24评分、SDSS评分,SCL-90评分中躯体化、人际关系敏感、抑郁、焦虑评分差值干预组均大于对照组,差异具有统计学意义(P<0.01);SCL-90评分中强迫、敌对、恐怖、偏执及精神病性因子分差值干预组和对照组差异无统计学意义(P>0.05)。结论药物联合正念认知疗法能够缩短患者平均住院时间,在促进患者抑郁症状恢复、改善社会功能和提高生活质量的康复获益影响上更具优势。
Objective To analyze the effects of drug combined with mindfulness-based cognitive therapy(MBCT)on rehabilitation benefits of depressive patients.Methods Depressed patients who were treated in the Psychosomatic Medicine department in the hospital from July 2019 to July 2020 were randomly assigned into intervention group(36 cases)and control group(34 cases),patients in intervention group received venlafaxine hydrochloride teatment and MBCT,patients in control-group received venlafaxine hydrochloride treatment.The Hamilton Depression Scale(HAMD-24),Self-rating Symptom Scale(SCL-90)and Social Disability Screening Scale(SDSS)were used to evaluate the depressive symptoms and the improvement of social function of patients in the two groups before and after hospitalization,and the cure rate and average length of hospital stay were compared between the two groups.Results①The average length of hospital stay in the intervention group(24.78±2.45 ds)and control group(29.02±2.24 ds),the difference was statistically significant(P<0.01).②The cure rate at discharge was 75.0%in the intervention group and 55.9%in the control group,which was higher than the control group,but the difference was not statistically significant(P>0.05).③HAMD-24,SDSS,and factors of SCL-90 scores showed no statistically significant difference between the two groups before intervention(P>0.05);After intervention,HAMD-24,SDSS and factors of SCL-90(Somatization,interpersonal sensitivity,depression,anxiety)score differences before and after the treatment in intervention group were higher than those in control group,difference was statistically significant(P<0.01);Factors of SCL-90(Coercion,hostility,terror,paranoia,and psychosis)score differences before and after the treatment between the two group was not statistically significant(P>0.05).Conclusion Drug combined with MBCT can shorten the average length of hospital stay,and has more advantages in promoting the recovery of depressive symptoms,improving social function and quality of life o
作者
刘刚正
张书友
韦欢
贾先荣
LIU Gangzheng;ZHANG Shuyou;WEI Huan;JIA Xianrong(Department of Psychosomatic Medicine,the 904th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force,Changzhou Jiangsu 213003)
出处
《常州实用医学》
2020年第4期216-220,共5页
CHANGZHOU PRACTICAL MEDICINE
关键词
药物
正念认知疗法
治疗
抑郁症
康复获益
影响
Drug
mindfulness-based cognitive therapy
Treatment
Depression
Rehabilitation benefits
impact
