摘要
目的分析山东省疟疾流行病学特征,为提高疟疾监测及诊治提供科学依据。方法收集2010-2017年山东省疟疾病例个案调查表和网络直报病例等监测数据,对疟疾的感染来源、虫种、人群和地区分布,发病及诊治等进行描述和统计学分析。结果2010-2017年山东省共报告疟疾病例1286例,其中恶性疟930例,间日疟208例,卵形疟86例,三日疟31例,未分型31例。共出现死亡病例8例。其中山东省原发感染57例,省外感染45例,境外输入性疟疾1184例。病例主要分布在泰安(203例)、济宁(156例)、烟台(138例)、威海(136例)、青岛市(111例)和菏泽(107例),占山东省疟疾病例的66.17%(851/1286)。男女性别比为30.37∶1,患者主要集中在21~50岁年龄组,共1225例(95.26%),以男性青壮年为主。职业分布农民最多(977例,75.97%)。国外输入病例最多的是赤道几内亚(262例),其次为安哥拉(208例),尼日利亚(128例)。2012首年度出现无本地感染病例,首次报告输入性卵形疟3例。结论山东省当前疟疾发病以国外输入性病例为主,且多数为恶性疟。输入性疟疾疫情严峻,应加强对外出非洲和东南亚地区务工回国人员疟疾监测,及时进行血检诊断和治疗输入性传染源。
Objective To analyze epidemiological characteristics of malaria and its trends in Shandong Province from 2010 to 2017 so as to provide scientific evidence for further improving malaria surveillance,diagnosis and treatment capabilities.Method Monitoring data of malaria cases and cases of direct online reporting in Shandong Province from 2010 to 2017 were collected.Descriptive Statistics were used to analyze the sources of infection,species of insects,population and regional distribution,incidence,diagnosis and treatment of malaria.Results From 2010 to 2017,a total of1286 malaria cases have been reported in Shandong Province,including 930 cases of Plasmodium falciparum,208 cases of Plasmodium vivax,86 cases of oval malaria,31 cases of Plasmodium vivax,and 31 cases of undifferentiated malaria.Among these cases,57 were primary infections in Shandong Province,45 were infected outside the province,and 1184 were imported malaria cases overseas.There were 8 deaths in total.The cases were mainly distributed in Taian(203 cases),Jining(156 cases),Yantai(138 cases),Weihai(136 cases),Qingdao City(111 cases)and Heze(107 cases),accounting for 66.17%of malaria cases in Shandong Province(851/1286).Majority of the cases were male young adults,with the male to female ratio of 30.37∶1.The patients were mainly concentrated in the 21 to 50 age group with a total of 1225 cases,accounting for 95.26%.As for the occupational distribution,977 cases were farmers,accounting for 75.97%of the total cases.The largest number of imported cases(262 cases)is from Equatorial Guinea,followed by208 cases in Angola and 128 cases in Nigeria.In 2012,there were no cases of local infections,and 3 cases of imported oval malaria were reported for the first time.Conclusion Current incidence of malaria in Shandong Province is dominated by foreign imported cases,and most of them are falciparum malaria.The epidemic situation of imported malaria is severe.It is necessary to strengthen malaria surveillance for workers returning home from Africa and Southeast Asi
作者
付婷霞
胡颖新
王用斌
FU Tingxia;HU Yingxin;WANG Yougbin(Shandong Institute of Parasitic Diseases,Shandong Institute of Parasitic Diseases,Gastroenterology-Hospital Affiliated to Shandong First Medical University,Shandong First Medical University&Shandong Academy of Medical Sciences,Jining 272033,Shandong Province,China)
出处
《寄生虫病与感染性疾病》
CAS
2020年第4期181-186,189,共7页
Parasitoses and Infectious Diseases
基金
中国全球基金疟疾项目实施性研究专项(项目编号:No.201201055)
世界卫生组织合作项目(项目编号:WP/2008/CHN)
山东省医学科学院科研基金面上项目(项目编号:No.201804)
徐州发明协会科技成果培育项目(项目编号:XAI201805)。
关键词
疟疾
输入性病例
流行特征
山东省
malaria
imported cases
epidemic characteristics
Shandong Province
