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胰腺癌危险因素及其与糖尿病相关性研究进展 被引量:8

Advance in the risk factors for pancreatic cancer and its correlation with diabetes
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摘要 胰腺癌是全球恶性度最高的癌症之一。总体5年生存率约6%。大量流行病学研究已经确定了某些危险因素,例如吸烟、肥胖、遗传、糖尿病、饮食、胰腺炎等。但其病因仍知之甚少,已知患有糖尿病的人罹患胰腺癌的风险增加,但很少有人研究评估糖胰腺癌合并尿病患者的预后。本文主要从胰腺癌的流行病学、危险因素、糖尿病与胰腺癌相关机制、胰腺癌合并糖尿病患者的预后进行综述。 Pancreatic cancer is one of the most malignant cancers in the world.The overall 5-year survival rate is approximately 6%.Extensive epidemiological studies have identified certain risk factors,such as smoking,obesity,genetics,diabetes,diet,pancreatitis,etc.However,the cause is still poorly understood,and people with known diabetes have an increased risk of pancreatic cancer,but few studies have evaluated the prognosis of patients with diabetes and pancreatic cancer.This article mainly described the epidemiology of pancreatic cancer,risk factors,the mechanism of diabetes and pancreatic cancer,and the prognosis of pancreatic cancer patients with diabetes.
作者 吕小斌 罗和生 LYU Xiaobin;LUO Hesheng(Department of Gastroenterology,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处 《胃肠病学和肝病学杂志》 CAS 2020年第12期1425-1430,共6页 Chinese Journal of Gastroenterology and Hepatology
关键词 流行病学 危险因素 糖尿病 胰腺癌 预后 Epidemiology Risk factors Diabetes Pancreatic cancer Prognosis
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