摘要
糖尿病足是糖尿病患者严重慢性并发症之一,常需要长时间治疗且难以愈合,致残、致死率高。随着对糖尿病足病理生理机制研究的深入,以自体富血小板血浆为代表的血小板浓缩物制剂应运而生,具有制备简便、有效避免免疫排斥反应、促进创面愈合、抗感染、费用低廉等优势,已作为糖尿病足的一种辅助治疗方式。同时,随着血小板浓缩物制剂本身的发展,目前已有富血小板血浆(PRP)、富血小板纤维蛋白(PRF)及浓缩生长因子(CGF)三代产品。本文就三代血小板浓缩物制剂在糖尿病足治疗的应用展开综述。
Diabetic foot diabetes is one of the serious chronic complications with high disability and mortality,which often requires long time treatment and is difficult to heal.With the further research on the pathophysiological mechanism of diabetic foot,platelet-rich concentrate represented by autologous platelet-rich plasma was produced.It has the advantages of simple preparation,effective avoidance of immune rejection,promotion of wound healing,anti-infection and low cost,and has been used as an auxiliary treatment for diabetic foot.At the same time,platelet-rich concentrate themselves are being developed.There are currently three generations of platelet-rich plasma(PRP),platelet-rich fibrin(PRF),concentrated growth factors(CGF),which have their own characteristics.This article reviews the application of three generations of platelet-rich concentrate in the treatment of diabetic foot.
作者
赵鹏宇
向小燕
ZHAO Peng-yu;XIANG Xiao-yan(Department of Plastic and Burns,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China)
出处
《川北医学院学报》
CAS
2020年第6期1113-1117,共5页
Journal of North Sichuan Medical College
基金
四川省2019年南充市市校科技战略合作专项(19SXHZ0059)。
