摘要
熟地黄、石菖蒲分别是重要的补血药、开窍药,两者均具有防治阿尔茨海默病(AD)的药理作用,亦能根据辨证配伍使用,其防治AD的机制主要有:抗氧化、抗炎、神经保护、调节中枢神经递质等。对近年熟地黄、石菖蒲治疗AD的作用机制进行综述,为进一步研究熟地黄、石菖蒲防治AD提供参考。
Rehmanniae Radix Praeparata and Acori Tatarinowii Rhizoma are crucial Chinese medicines for replenishing blood and resuscitation,respectively.Both of them show the pharmacological effects on preventing and treating Alzheimer’s disease(AD).They can also be compatibly used according to syndrome differentiation.Their mechanisms on the prevention and treatment of AD mainly include anti-oxidation,anti-inflammation,neuroprotection,regulation on central neurotransmitters and so on.This article reviews the mechanisms of Rehmanniae Radix Praeparata and Acori Tatarinowii Rhizoma in the treatment of AD in recent years,so as to provide reference for further study of their prevention and treatment on AD.
作者
胡鹏跃
李国文
谢燕
HU Pengyue;LI Guowen;XIE Yan(Shanghai University of Traditional Chinese Medicine,Shanghai 201203.China;Shanghai TCM-Integrated Hospital,Shanghai 200082,China)
出处
《上海中医药大学学报》
CAS
2020年第6期99-104,共6页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
上海市科委优秀学术带头人资助项目(19XD1423700)。
关键词
熟地黄
石菖蒲
阿尔茨海默病
作用机制
综述
Rehmanniae Radix Praeparata
Acori Tatarinowii Rhizoma
Alzheimer’s disease
mechanism
review
