摘要
为更好地控制小鹅瘟的发生,探究疫苗免疫及抗体注射对雏鹅小鹅瘟的预防效果。将200只1日龄试验鹅随机分成4组,其中A组为疫苗组,B组为卵黄抗体+疫苗组,C组为卵黄抗体组,D组为对照组。对试验鹅分别于1日龄、7日龄进行注射,并在首免后第7、14、21及28天检测小鹅瘟抗体。结果显示:在第7天,B组和C组的免疫抗体平均效价均高于A组;在第14天,B组抗体平均效价出现明显下降,均低于A组和C组。在第21~28天,A组和B组均保持较高的抗体水平,而C组抗体效价下降较快。结果提示,在没有母源抗体保护的情况下,对于雏鹅小鹅瘟多发高发的地区和场群,建议1日龄、7日龄均注射卵黄抗体加以预防;对于雏鹅发病日龄明显增加,超过20日龄仍有发病的地区和场群,建议1日龄、7日龄均免疫小鹅瘟疫苗加以防控。
In order to better control gosling plague,the effects of vaccination and antibody injection were studied.200 one-day-old geese were randomly divided into four groups:group A was to be vaccinated twice,group B was to be injected egg-yolk antibodies and vaccinated respectively,group C was to be injected with egg-yolk antibodies twice and group D was considered as a control group.The geese were injected at 1 and 7 days of age,respectively,and their antibodies were detected at 0(prior to vaccination),7,14,21 and 28 days.The results showed that on the 7th day,the average titers of the antibodies of groups B and C were higher than those of group A;on the 14th day,the average titers of the antibodies of group B decreased significantly,which were lower than those of groups A and C.From the 21st to the 28th day,the average level of antibodies remained higher in groups A and B,and the antibody titer decreased rapidly in group C.For the purpose of disease control,it was suggested to inject egg-yolk antibodies respectively at 1 and 7 days of age in the regions and farms with high incidence of gosling plague in the absence of maternal antibody protection;and to vaccinate respectively at 1 and 7 days of age in the regions and farms where geese were still infected with the disease after 20 days old.
作者
邱冬
吴坤
徐小艳
董永毅
蒋彩霞
朱水明
杨杨
胡圣林
Qiu Dong;Wu Kun;Xu Xiaoyan;Dong Yongyi;Jiang Caixia;Zhu Shuiming;Yang Yang;Hu Shenglin(Jiangsu Provincial Animal Disease Control Center,Nanjing,Jiangsu 210036,China;Zhenjiang Provincial Animal Disease Control Center,Zhenjiang,Jiangsu 212000,China;Jurong Animal Husbandry and Veterinary Station,Jurong,Jiangsu 212400,China)
出处
《中国动物检疫》
CAS
2021年第1期112-114,共3页
China Animal Health Inspection
基金
江苏现代农业(水禽)产业技术体系疾病防控创新团队项目(JATS〔2019〕345)。
关键词
小鹅瘟
疫苗注射
卵黄抗体
效果比较
gosling plague
vaccine injection
egg-yolk antibody
comparison of immune effect
