摘要
为建立药物检验中滴定液标定的不确定度评定方法,依据《中国药典》2015年版四部及《中国药品检验标准操作规范》,配制并标定氢氧化钠滴定液的浓度,分析来自于对照品的取样、溶液的配制过程、仪器测定过程以及测量的重复性等各种不确定度影响因素,并对其进行评估。氢氧化钠滴定液的标定结果为(0.1017±0.0002)mol/L,第二项为影响因子k=2的扩展不确定度。
To establish the uncertainty evaluation method for calibration of titrant in drug inspection,the sodium hydroxide titrant was prepared and calibrated according to the Ch.P 2015 volume IV and the Chinese Standard Operating Code for Drug Inspection.The factors affecting the uncertainty,including the sampling process of the standard substance,titration,measurement repeatability,and calculation of the measurement,were analyzed and evaluated.The calibration result of sodium hydroxide titrant was(0.1017±0.0002)mol/L,and the second term was the expanded uncertainty with the coverage factor as 2.
作者
符秀娟
陈俊波
傅琪彦
林丽珍
FU Xiu-juan;CHEN Jun-bo;FU Qi-yan;LIN Li-zhen(Hainan College of Vocation&Technique,Hainan Haikou 570216,China)
出处
《广州化工》
CAS
2020年第24期100-101,118,共3页
GuangZhou Chemical Industry
关键词
氢氧化钠滴定液
标定
不确定度
sodium hydroxide titrant
calibration
uncertainty
