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30岁及以上女性高危型人乳头瘤病毒阳性、宫颈细胞学阴性310例临床分析 被引量:2

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摘要 目的探讨年龄≥30岁高危型人乳头瘤病毒(HPV)阳性而宫颈细胞学阴性患者HPV亚型分布及宫颈上皮内病变情况。方法收集hrHPV和宫颈液基细胞学联合宫颈癌筛查结果中,高危型HPV阳性/细胞学阴性且年龄≥30岁患者310例,分析其HPV亚型分布及不同亚型组的病理结果。结果 310例患者中,HPV16阳性71例(22.9%),HPV18阳性24例(7.8%),其他12种高危型HPV亚型阳性215例(69.4%)。阴道镜下活检高级别宫颈上皮内病变(HSIL)检出率15.8%(49/310),其中HPV16阳性/细胞学阴性患者宫颈HSIL检出率19.7%(14/71)。结论年龄≥30岁hrHPV阳性/细胞学阴性患者仍有较高比例的HSIL,除了HPV16/18,其他12种高危型HPV持续感染也应及时行阴道镜检查,以期早发现病变。
出处 《中国妇产科临床杂志》 CSCD 北大核心 2020年第6期621-622,共2页 Chinese Journal of Clinical Obstetrics and Gynecology
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