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淋巴细胞/单核细胞比值与肝癌患者肝动脉化疗栓塞术预后的相关性 被引量:2

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摘要 目的探讨术前淋巴细胞/单核细胞比值(LMR)预测经肝动脉化疗栓塞术(TACE)治疗肝癌患者预后的临床价值。方法回顾性分析接受单一TACE治疗的肝癌患者124例的临床及随访资料,依据LMR的临界值分为LMR<3.272组和LMR≥3.272组。按照多因素和单因素进行判别,TACE治疗后,分析肝癌患者总生存期(OS),根据Kaplan-Meier法分析中位生存时间,利用Log-rank非参数检验方式分析生存率的曲线。结果124例中5年内死亡100例,肝癌患者LMR≥3.272组术后1、3、5年OS明显高于LMR<3.272组(P<0.05);单因素和多因素预后分析结果均显示LMR、肿瘤数量及门静脉栓塞与肝癌患者的OS均有显著相关性(均P<0.05)。结论术前LMR可作为TACE治疗肝癌患者预后的独立预测指标,术前LMR高的患者其预后较差。
作者 庄严 李成浩
出处 《中国老年学杂志》 CAS 北大核心 2020年第24期5192-5195,共4页 Chinese Journal of Gerontology
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