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基于医学影像技术的3D打印临床应用与突破 被引量:22

Clinical application and breakthrough of three-dimensional printing based on medical imaging technology
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摘要 背景:3D打印作为影像技术“实体化”的延伸,两者之间密不可分。为了满足临床应用需求,不同成像原理的影像技术与3D打印结合使得其在医学应用上有了更多可能。目的:总结不同成像原理影像技术与3D打印结合在医学方面应用的研究进展,并对其优缺点进行综述分析。方法:在Web of science、PubMed、CNKI、SinoMed及万方数据库,使用主题词“3D printed,Three-dimensional printing,Additive Manufacturing,Ultrasonography,Ultrasound,MRI,Magnetic Resonance Imaging,CT,Computed Tomography,PET/CT,SPECT/CT,Radiotherapy,Digital Subtraction,DSA,3D打印,超声检查,磁共振成像,放疗,核医学”等检索近5年内相关文献,最终纳入61篇进行综述。结果与结论:①基于不同类型影像数据的3D打印医学应用主要分为临床应用、设备应用及教学应用,讨论不同影像数据源的优缺点,并概述了当前不同影像技术与3D打印结合应用的难点;②目前医学3D打印技术基于放射原理成像成型的临床应用较广,并且使用相对成熟;③而随着3D打印技术应用的深入,非电离成像方式MRI、超声也在应用中展现出较大潜力。 BACKGROUND:As an extension of the“materialization”of image technology,three-dimensional(3D)printing is inseparable between the two.To meet the needs of clinical application,the combination of different principles of imaging technology and 3D printing technology makes it more possible in medical application.OBJECTIVE:To summarize the progress of medical application research of the combination of different imaging principles and 3D printing,and analyze its advantages and disadvantages.METHODS:The relevant articles from the databases of Web of Science,PubMed,CNKI,SinoMed and Wanfang were searched by computer.The subject headings“3D printed,Three-dimensional printing,Additional Manufacturing,Ultrasonography,Ultrasound,MRI,Magnetic Resonance Imaging,CT,Computed Tomography,PET/CT,SPECT/CT,Radiotherapy,Digital Subtraction,DSA”in English and“3D printing,ultrasound,MRI,radiotherapy,nuclear medicine”in Chinese were retrieved in the past five years,and finally 61 articles were included for review.RESULTS AND CONCLUSION:(1)This paper summarizes the medical application of 3D printing based on different types of image data,which is mainly divided into clinical application,equipment application and teaching application.The advantages and disadvantages of different image data sources are discussed and the difficulties in the combination of the two are summarized.(2)At present,the clinical application of medical 3D printing based on radiological imaging is wide,and the use is relatively mature.(3)With the in-depth application of 3D printing technology,non-ionized imaging methods such as MRI and ultrasound also show great potential in the application.
作者 杜雪婷 杨洋 黄文华 陈武标 Du Xueting;Yang Yang;Huang Wenhua;Chen Wubiao(Department of Radiology,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524001,Guangdong Province,China;National Key Discipline of Human Anatomy of School of Basic Medicine of Southern Medical University,Guangdong Key Laboratory of Medical Biomechanics,Guangdong Medical 3D Printing Application and Transformation Engineering Technology Research Center,Guangdong Medical 3D Printing Application Transformation Innovation Platform,Guangzhou 510515,Guangdong Province,China;Department of Orthopedics,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524001,Guangdong Province,China)
出处 《中国组织工程研究》 CAS 北大核心 2021年第18期2887-2894,共8页 Chinese Journal of Tissue Engineering Research
基金 国家重点研发计划(2017YFC1103400),项目负责人:黄文华 广东省科技计划项目(2017B090912006),项目参与人:黄文华 深圳市医疗卫生“三名工程”高层次医学团队(SZSM201612019),项目参与人:黄文华。
关键词 3D打印 医学影像 X射线 非电离成像 放射性核素显像 综述 3D printing medical imaging X-ray imaging non-ionizing imaging radionuclide imaging review
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