摘要
目的探讨糖尿病患者体位性低血压发生情况及其相关危险因素。方法选取2018年1月至2019年9月就诊于本院的2型糖尿病(T2DM)患者230例为研究对象,统计患者是否发生体位性低血压,并分析T2DM患者发生体位性低血压的危险因素。结果 230例T2DM患者中发生体位性低血压79例(34.35%);体位性低血压组患高血压与糖尿病肾病比例、糖化血红蛋白水平、卧位收缩压水平分别为74.68%、44.30%、(9.42±2.28)%、(152.24±18.69)mmHg,高于非体位性低血压组,肾小球滤过率低于非体位性低血压组,差异有统计学意义(P<0.05);两组性别、年龄、病程、体重指数、卧位舒张压、尿素氮、血肌酐以及合并糖尿病周围神经病变、脑血管病、冠心病比例比较差异无统计学意义;Logistic回归分析显示,高血压、糖尿病肾病、糖化血红蛋白、卧位收缩压是糖尿病患者发生体位性低血压的独立危险因素(P<0.05且OR≥1)。结论 T2DM患体位性低血压比例较高,其发生与高血压、糖尿病肾病、糖化血红蛋白、卧位收缩压密切相关,临床需加以重视,及时实施针对性的措施干预,以改善患者预后。
Objective To investigate the incidence of orthostatic hypotension and its related risk factors in diabetic patients.Methods 230 patients with type 2 diabetes mellitus(T2DM)who were treated in our hospital from January 2018 to September 2019 were selected as the study subjects.The occurrence of postural hypotension in patients with type 2 diabetes mellitus was counted,and the risk factors of postural hypotension in patients with type 2 diabetes mellitus were analyzed.Results 79 cases of orthostatic hypotension occurred in 230 patients with T2DM(34.35%);the proportion of hypertension and diabetic nephropathy,glycated hemoglobin level and supine systolic blood pressure in the orthostatic hypotension group were 74.68%,44.30%,(9.42±2.28)%,(152.24±18.69)mmHg,higher than the non-postural hypotensive group,glomerular filtration rate was lower than non-post position hypotension group,and the difference was statistically significant(P<0.05).There was no statistically significant difference between the two groups in terms of gender,age,course of disease,body mass index,horizontal diastolic blood pressure,urea nitrogen,serum creatinine,and the proportion of patients with diabetic peripheral neuropathy,cerebrovascular disease and coronary heart disease.Logistic regression analysis showed that hypertension,diabetic nephropathy,glycosylated hemoglobin,and supine systolic blood pressure were independent risk factors for orthostatic hypotension in diabetic patients(P<0.05 and OR≥1).Conclusion T2DM has a high proportion of orthostatic hypotension,and its occurrence is closely related to hypertension,diabetic nephropathy,glycosylated hemoglobin,supine systolic blood pressure,clinical attention needs to be paid,and targeted interventions are implemented in time to improve the prognosis of patients.
作者
虞成毕
严东标
邱悦
刘浩
陈勇
Yu Chengbi;Yan Dongbiao;Qiu Yue;Liu Hao;Chen Yong(Department of Diabetes,Jiujiang City Hospital of Traditional Chinese Medicine,Jiujiang,Jiangxi,332000,China)
出处
《当代医学》
2020年第35期96-98,共3页
Contemporary Medicine
关键词
体位性低血压
糖尿病
危险因素
高血压
Orthostatic hypotension
Diabetes
Risk factors
Hypertension
