摘要
目的探究三焦次第疗法治疗血管性痴呆对患者神经功能缺损及行为能力的影响。方法选取2016年7月—2018年12月(广西中医药大学第一附属医院、宾阳县中医医院及桂林市中医医院)收治的血管性痴呆患者150例,按随机数字表法分为对照组与观察组,各75例。对照组采用血管性痴呆西医常规治疗,观察组在对照组的基础上联合三焦次第疗法治疗,1个月后进行疗效评估。对比两组患者临床疗效,评估两组患者治疗前后中医证候积分、认知功能、日常生活能力、神经功能缺损情况变化。结果观察组患者临床总有效率为92.00%(69/75),较对照组的66.67%(50/75)显著升高(P<0.01);与治疗前比,治疗后两组患者SDSVD评分、NFDS评分、ADL评分、BBS评分显著降低,且观察组显著低于对照组(P<0.01);两组患者MMSE评分显著升高,且观察组显著高于对照组(P<0.01)。结论三焦次第疗法可显著缓解血管性痴呆患者临床症状,改善其神经功能,提高其行为能力,临床疗效显著优于西医常规治疗。
Objective To explore the effect of triple-Jiao sequence therapy on the neurologic deficits and behavior ability in the treatment of vascular dementia. Methods A total of 150 vascular dementia patients in our hospital from Jul. 2016 to Dec. 2018 were selected and divided into control group and observation group according to random number table, 75 cases in each group. The control group was treated with conventional western medicine treatment of vascular dementia and the observation group was treated combined with triple-Jiao sequence therapy on the basis of control group. We evaluated the curative effect 1 month after treatment. The clinical curative effect of two groups were compared. The TCM syndrome integral, cognitive function and daily life ability, and nerve function defect situation changes of patients in two group before and after treatment were evaluated. Results The clinical effectin observation group was 92.00%(69/75), which was significantlyhigher than that 66.67%(50/75) of the control group(P<0.01). Compared with those before treatment, the SDSVD score, NFDS score, ADL score and BBS score in two groups after treatment decreased significantly, and those of the observation group weresignificantlylower than those of the control group(P<0.01). The MMSE scores of patients in two groups increased significantly, and that of the observation group was significantlyhigher than that of the control group(P<0.01). Conclusion Triple-Jiao sequence therapy can alleviate the clinical symptoms of patients with vascular dementia significantly, improve the nerve function and enhance the behavior ability, and the clinical efficacy is significantly superior to the effect of conventional western medicine treatment.
作者
陈炜
胡跃强
吴林
肖榕
陆岸英
陈华丽
韦华军
唐农
CHEN Wei;HU Yueqiang;WU Lin;XIAO Rong;LU Anying;CHEN Huali;WEI Huajun;TANG Nong(Brain Disease Zone,The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530023,Guangxi,China;Chinese Medicine Science Experimental Center,Guangxi University of Chinese Medicine,Nanning 530001,Guangxi,China;Brain Disease Division,Guilin Hospital of Traditional Chinese Medicine,Guilin 541002,Guangxi,China;Brain Disease Department,Binyang County Chinese Medicine Hospital,Nanning 530400,Guangxi,China)
出处
《中华中医药学刊》
CAS
北大核心
2020年第11期70-73,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金(81874453)
广西科技计划项目重点研发计划(AB16380324)
广西中医基础研究重点实验室系统项目(16-380-58-06)。
关键词
血管性痴呆
三焦次第疗法
神经功能缺损
行为能力
疗效
vascular dementia
triple-Jiao sequence therapy
nerve function defect
behavior ability
effect
