摘要
目的分析老年急性胰腺炎(AP)患者医院感染特点及其危险因素,为开展干预措施提供依据。方法回顾性收集2012年1月至2018年12月某院消化内科老年AP患者临床基线资料,分析感染患者临床特点及其危险因素。结果共收集老年AP患者206例,发生感染76例,感染率为36.89%。感染部位以下呼吸道、腹腔感染为主,分别占38.55%、31.33%。感染部位检出的102株病原菌中革兰阴性菌、革兰阳性菌以及真菌分别占70.59%、26.47%、2.94%,革兰阴性菌分布以铜绿假单胞菌检出率排首位,革兰阳性菌以金黄色葡萄球菌检出率最高。多因素分析结果显示,低氧血症、入住ICU、APACHEII≥8分、糖尿病是老年AP患者发生感染的独立危险因素(P<0.05)。结论老年AP患者医院感染率较高,检出病原菌主要以革兰阴性杆菌为主,多种因素与其感染发生密切相关,医务人员应当及时采取有针对性的感染防控措施。
Objective To analyze the characteristics and risk factors of nosocomial infection in elderly patients with acute pancreatitis(AP),and provide a basis for intervention measures.Methods The clinical baseline data of elderly AP patients in the gastroenterology department of a hospital from January 2012 to December 2018 were retrospectively collected,and the clinical characteristics and risk factors of infected patients were analyzed.Results A total of 206 elderly AP patients were enrolled,and 76 cases were infected with an infection rate of 36.89%.Lower respiratory tract and abdominal cavity infections were the main infection sites,accounting for 38.55%and 31.33%,respectively.Among 102 strains of pathogenic bacteria detected at the site of infection,Gram-negative bacteria,Gram-positive bacteria and fungi accounted for 70.59%,26.47%,and 2.94%,respectively.Among the Gram-negative bacteria,the detection rate of Pseudomonas aeruginosa was ranked first,and among the Gram-positive bacteria,the detection rate of Staphylococcus aureus was the highest.Multivariate analysis showed that hypoxemia,ICU admission,APACHE II≥8 points,and diabetes were independent risk factors for infection in elderly AP patients(P<0.05).Conclusion The nosocomial infection rate of elderly AP patients was relatively high.The main pathogens detected were Gram-negative bacilli,and many factors were closely related to infection.Medical staff should take timely targeted infection prevention and control measures.
作者
邢芳芳
廖鸿俊
邢颖
周建红
薛珊
XING Fang-fang;LIAO Hong-jun;XING Ying;ZHOU Jian-hong;XUE Shan(Hospital of the 72 th Group Army,PLA,Huzhou Zhejiang 313000,China)
出处
《中国消毒学杂志》
CAS
2020年第10期771-773,777,共4页
Chinese Journal of Disinfection
关键词
老年患者
急性胰腺炎
医院感染
危险因素
elderly patients
acute pancreatitis
nosocomial infection
risk factors
