摘要
目的探讨腹腔镜术后联合促性腺激素释放激素类似物(GnRH-a)对防止子宫内膜异位症(EMT)复发与妊娠的影响。方法选取2018年4月-2019年4月在我院行腹腔镜手术治疗的EMT患者100例为研究对象,采用计算机程序生成随机数的方法分为对照组(n=49)及观察组(n=51)。对照组行腹腔镜手术,观察组术在此基础上联合GnRH-a,比较分析2组疗效、复发及妊娠率。结果观察组治疗总有效率比对照组高(P<0.05);观察组复发率比对照组低,但未见明显差异(P>0.05);观察组妊娠率比对照组高(P<0.05)。结论腹腔镜术后给予GnRH-α治疗可有效提高EMT的治疗效果,维持雌激素于低水平状态,提高妊娠率,降低疾病复发。
Objective To investigate the effect of combined gonadotropin-releasing hormone analogue(GnRH-a)on prevention of endometriosis(EMT)recurrence and pregnancy after laparoscopic surgery. Methods 100 patients with EMT who underwent laparoscopic surgery in our hospital from April 2018 to April 2019 were selected as the research subjects. According to the method of random number generation by computer program, they were divided into a control group(n=49)and an observation group(n=51). The control group underwent laparoscopic surgery, and the observation group combined with GnRH-a on this basis. Compared and analyzed the efficacy, recurrence and pregnancy rate of the two groups. Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05);the recurrence rate of the observation group was lower than that of the control group, but no obvious difference was found(P>0.05), and the pregnancy rate was higher than that in the control group(P<0.05).Conclusion GnRH-α treatment of patients after laparoscopic surgery can effectively improve the therapeutic effect of EMT, maintain low estrogen status, promote their recovery, increase pregnancy rate, and reduce disease recurrence.
作者
余镜春
占春晓
谢莉萍
Yu Jingchun;Zhan Chunxiao;Xie Liping(The People's Hospital of Boyang County,Boyang,Jiangxi 333100)
出处
《基层医学论坛》
2020年第34期4894-4895,共2页
The Medical Forum
基金
江西省卫生健康委科技计划(20204330)。
