摘要
目的:观察玻璃体切割术(PPV)联合内界膜(ILM)剥除术治疗顽固性糖尿病黄斑水肿的临床疗效。方法:回顾性分析顽固性糖尿病黄斑水肿并行PPV联合ILM剥除术患者56例56眼,根据有无后极部玻璃体后脱离分为A组(无玻璃体后脱离,35例35眼)和B组(有玻璃体后脱离,21例21眼)。对比分析手术前及手术后1、3、6mo时患眼最佳矫正视力(BCVA)、黄斑中心视网膜厚度(CMT)变化情况。结果:A组手术后1、3、6mo平均CMT和BCVA与手术前比较均有差异(P<0.05)。B组手术后1、3、6mo平均BCVA与手术前比较均无差异(P>0.05);手术后1mo平均CMT与手术前比较有差异(P<0.05),术后3、6mo平均CMT与手术前比较均无差异(P>0.05)。术后1、3、6mo,两组CMT、BCVA比较均有差异(P<0.05)。结论:PPV联合ILM剥除术能有效治疗无玻璃体后脱离的顽固性糖尿病黄斑水肿,提高患者视力;但当患者玻璃体已经后脱离且没有牵拉时,PPV联合ILM剥除术治疗效果不佳。
AIM:To observe the clinical effect of vitrectomy(PPV)combined with internal limiting membrane(ILM)peeling in the treatment of refractory diabetic macular edema.METHODS:The data of 56 eyes(56 patients)with refractory diabetic macular edema accepted PPV combined with ILM peeling were collected and retrospectively analyzed.The patients were divided into Group A(no posterior vitreous detachment):35 cases(35 eyes)and Group B(with posterior vitreous detachment):21 cases(21 eyes).The best corrected visual acuity(BCVA)and central macular thickness(CMT)before and 1,3,6mo after operation were compared and analyzed.RESULTS:The mean CMT and LogMAR BCVA of Group A at 1,3 and 6mo after operation were significantly different from those before operation(P<0.05);There was no significant difference in BCVA between those before and 1,3,6mo after operation in Group B(P>0.05).The mean CMT of 1mo after operation was significantly different from that before operation(P<0.05).There was no significant difference in mean CMT between 3 and 6mo after operation and before operation(P>0.05).CMT and BCVA were significantly different between the two groups at 1,3 and 6mo postoperatively(P<0.05).CONCLUSION:PPV combined with ILM peeling can effectively treat refractory diabetic macular edema without posterior vitreous detachment,improve the patient’s vision;However,PPV combined with ILM peeling was not effective in patients without posterior vitreous detachment.
作者
张聪
许贺
徐丽
Cong Zhang;He Xu;Li Xu(Department of Ophthalmology,the Fourth People's Hospital of Shenyang, Shenyang 110031, Liaoning Province, China)
出处
《国际眼科杂志》
CAS
北大核心
2020年第12期2159-2162,共4页
International Eye Science
基金
辽宁省自然科学基金指导计划(No.2018011263-301)。
关键词
玻璃体切割
内界膜剥除
糖尿病黄斑水肿
玻璃体后脱离
vitrectomy
internal limiting membrane peeling
diabetic macular edema
posterior vitreous detachment
