摘要
To the Editor:Many well-studied sonographic features have been used clinically to evaluate thyroid nodules for malignancies.Sonographic grayscale features proposed by the American College of Radiology Thyroid Imaging,Reporting and Data System(TI-RADS)include composition,echogenicity,shape,margin,and echogenic foci.[1]Other features,such as vascularity imaging,have gradually been recognized by sonographers.Sustained angiogenesis results in tumor-specific vasculature compared to normal tissues in the context of architecture and biological behavior.[2]Tumor neovascularization shows abnormal maturation,manifesting irregular sprouting,and branching of angiogenic vessels with disordered coverage of pericytes.Therefore,vascularity is critical for the evaluation of malignancy in thyroid nodules.
基金
a grant from the Natural Science Foundation of Liaoning Province(No.201602221)。
