摘要
过渡金属催化的不对称氧化反应,作为不对称合成的重要研究内容之一,为手性天然产物和药物的合成提供了实用便捷途径,因此其方法研究备受人们关注.重点介绍了近年来过渡金属催化的烯烃不对称氧化官能团化反应、C—H键不对称氧化反应、不对称BV氧化反应和硫醚不对称氧化反应等研究进展,并展望其未来发展趋势.
Transition metal-catalyzed asymmetric oxidation,as one of important research targets of chiral synthesis,provides a direct,practical route for the synthesis of various chiral bioactive products and drugs,and has received much attention.The recent progress of the methods of transition metal-catalyzed asymmetric oxidation,especially,asymmetric oxidative functionalization of olefins,C-H bond asymmetric oxidation reaction,asymmetric BV oxidation and sulfide asymmetric oxidation is elaborated.Outlook of those issuesis is also discussed.
作者
姚彪
巫佳浩
汪钰
江焕峰
Yao Biao;Wu Jiahao;Wang Yu;Jiang Huanfeng(Key Laboratory of Functional Molecular Engineering of Guangdong Province,School of Chemistry and Chemical Engineering,South China University of Technology,Guangzhou 510641)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2020年第10期3044-3064,共21页
Chinese Journal of Organic Chemistry
基金
国家重点研发计划(No.2016YFA06002900)
广东省重点领域研发(No.2020B010188001)资助项目。
关键词
过渡金属催化
不对称氧化
对映选择性
烯烃
碳-氢活化
transition metal catalysis
asymmetric oxidation
enantioselectivity
olefin
C-H activation
