摘要
目的:总结慢性阻塞性肺疾病(COPD)急性加重期经鼻高流量氧疗期间营养不良的影响因素。方法:选取80例经鼻高流量氧疗的COPD急性加重期患者,根据微型营养评估量表分为营养不良组(<17分)50例及营养良好组(≥24分)30例,对2组基本资料进行对比,行Logistic回归分析,总结影响COPD急性加重期经鼻高流量氧疗期间营养不良的独立风险因素。结果:2组患者性别、居住地区、婚姻状态、居住状态、文化程度、医疗费用承担方式、月收入、吸烟情况、饮酒情况、运动情况、1年内急性加重次数、骨质疏松症发生率比较,差异无统计学意义(均P>0.05),年龄、病程、1年内住院时间、焦虑程度、抑郁程度、疾病严重程度比较,差异有统计学意义(均P<0.05);Logistic回归分析提示:年龄、病程、焦虑程度、疾病严重程度为COPD急性加重期经鼻高流量氧疗期间营养不良的独立风险因素(OR分别为:1.285、1.302、1.388、1.432,P<0.05);与营养良好组比较,营养不良组住院时间更长、并发症发生率更高(均P<0.05)。结论:年龄、病程、焦虑程度、疾病严重程度为COPD急性加重期经鼻高流量氧疗期间营养不良的独立风险因素。
Objective:To summarize the influencing factors of malnutrition during nasal high-flow oxygen therapy in the acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods:A total of 80 patients with acute exacerbation of COPD who received nasal high-flow oxygen therapy were selected and divided into malnutrition group(<17 points,n=50)and well-nourished group(≥24 points,n=30)according to the results of the micronutrition assessment scale.The basic data of the two groups were compared,and factors with statistical differences were substituted into the logistic regression analysis model to summarize the independent risk factors influencing the malnutrition during nasal high-flow oxygen therapy in the acute exacerbation of COPD.Results:There was no significant differences in gender,residential area,marital status,living status,educational level,medical expenses,monthly income,smoking status,drinking status,exercise status,times of acute exacerbation within one year and incidence of osteoporosis between two groups(all P>0.05).There were statistical differences in age,duration of disease,length of hospitalization within one year,degree of anxiety and depression,and severity of disease between two groups(all P<0.05).Logistic regression analysis suggested that age,duration of disease,degree of anxiety,and severity of disease were independent risk factors for malnutrition during nasal high-flow oxygen therapy in acute exacerbation of COPD(OR:1.285,1.302,1.388,1.432,P<0.05).The hospitalization time in the malnourished group was significantly longer,and the incidence of complications was significantly higher than in the well-nourished group(all P<0.05).Conclusion:Age,duration of disease,anxiety and disease severity are independent risk factors for malnutrition during nasal high-flow oxygen therapy in acute exacerbation of COPD.
作者
时靖峰
韩明锋
滕小宝
张小华
SHI Jing-feng;HAN Ming-feng;TENG Xiao-bao;ZHANG Xiao-hua(Second People's Hospital of Fuyang City,Fuyang 236015,China)
出处
《内科急危重症杂志》
2020年第5期380-382,393,共4页
Journal of Critical Care In Internal Medicine
关键词
慢性阻塞性肺疾病急性加重期
经鼻高流量氧疗
营养不良
Acute exacerbation of chronic obstructive pulmonary disease
Transnasal high-flow oxygen therapy
Malnutrition
