摘要
目的分析行腹腔镜手术治疗的子宫内膜异位症(EMS)Ⅲ、Ⅳ期患者联合注射亮丙瑞林治疗对卵巢功能及临床症状的影响。方法选取2018年1月至2019年1月本院收治的EMSⅢ、Ⅳ期患者64例,随机分为常规组和研究组,各32例。常规组采用腹腔镜手术治疗,研究组联合皮下注射亮丙瑞林治疗。比较两组治疗总有效率、卵巢功能及排卵率。结果研究组治疗后FSH、LH和E2水平显著低于常规组(均P<0.01),排卵率显著高于常规组(75.0%比43.75%),且卵巢体积明显缩小[(3.8±0.3)cm3比(7.6±0.7)cm3],差异具有统计学意义(P<0.01)。常规组显效12例,有效10例,研究组分别为20例及10例,研究组有效率更高(P<0.01)。结论EMSⅢ、Ⅳ期患者采取腹腔镜手术联合亮丙瑞林治疗有助于卵巢修复,改善临床症状,提高治疗有效率。
Objective To analyze the effects of injection of lepredrin on ovarian function and clinical symptoms in patients with endometriosis(EMS)stageⅢandⅣtreated by laparoscopic surgery.Methods 64 stageⅢandⅣEMS patients admitted to our hospital from January,2018 to January,2019 were randomly divided into a conventional group and a study group,with 32 cases in each group.Both groups were treated by laparoscopic surgery;in addition,the study group took lepredrin.The total response rates,ovarian function,and ovulation rates of the two groups were compared.Results After the treatment,the levels of FSH,LH,and E2 in the study group were significantly lower than those in the conventional group(all P<0.01).The ovulation rate was significantly higher and the ovarian volume was significantly lower in the study group than in the conventional group[75.0%vs.43.75%and(3.8±0.3)cm3 vs.(7.6±0.7)cm3;both P<0.01].In the conventional group,12 cases were markedly effective,and 10 cases were effective;and in the study group,20 and 10 cases;the effective rate of the study group was higher(P<0.01).Conclusion ForstageⅢandⅣEMS patients,laparoscopic surgery combined with lepredrin is helpful for ovarian repair and improvement of clinical symptoms and treatment efficacy.
作者
陆盛安
郝辰珺
Lu Sheng'an;Hao Chenjun(He Xian Memorial Hospital,Panyu District,Guangzhou511400,China)
出处
《国际医药卫生导报》
2020年第22期3471-3473,共3页
International Medicine and Health Guidance News
