摘要
目的:分析毛细支气管炎住院婴儿的临床和病原学特征。方法:198例毛细支气管炎作为研究组,135例支气管肺炎住院患儿作为对照组,收集并比较2组患儿的一般资料(年龄、性别、早产史、既往喘息史、住院时间及入院病情)、比较2组患儿入院时的体征、血液生化检查结果及影像学特征,比较2组患儿的病原学检查结果[8种常见呼吸道病原和Epstein-Barr病毒(EBV)检出及痰细菌培养等情况]。结果:研究组住院患儿年龄明显小于对照组,男性比例、住院时间及入院时重症病例分别多于对照组(P<0.05或P<0.01);与对照组比较,研究组住院患儿三凹征检出率、外周血血小板计数、心肌相关标志物N端脑利钠肽前体水平及双肺病变阳性率增高,但发热检出率、左肺病变阳性率及支原体检出率降低(P<0.05或P<0.01)。结论:与支气管肺炎相比,毛细支气管炎住院患儿的年龄较小、男性较常见、住院时间较长、病情较重,2组患儿病原检出情况无明显差异。
Objective:To analyze the clinical and etiological characteristics of hospitalized infants with bronchiolitis.Methods:198 cases of bronchiolitis were study group and 135 cases of bronchopneumonia were control group.The general data of 2 groups was collected and compared(age,sex,history of preterm birth,history of past wheezing,length of stay and admission).The physical signs,blood biochemical examination results and imaging features of 2 groups were compared.The results of etiological examination were compared between the two groups[8 common respiratory pathogens and Epstein-Barr virus(EBV)detection and sputum bacterial culture].Results:The age of hospitalized children in the study group was significantly lower than that in the control group,and the proportion of men,the length of stay and the severe cases in the study group were higher than those in the control group(P<0.05 or P<0.01).Compared with the control group,the detection rate of the three concave sign,the peripheral blood platelet count,the NT-proBNP level of myocardial related markers and the positive rate of bilateral lung lesions in the hospitalized children in the study group increased,but the detection rate of fever,the positive rate of left lung disease and the rate of mycoplasma examination decreased(P<0.05 or P<0.01).Conclusion:Compared with bronchopneumonia,the children with bronchiolitis are younger,more common in men,longer in hospital and more serious in illness,and there is no significant difference in pathogen detection between the two groups.
作者
蒙文娟
朱晓萍
李波
杨俊
张亚莉
罗婧
王雪松
王友艳
余漪漪
MENG Wenjuan;ZHU Xiaoping;LI Bo;YANG Jun;ZHANG Yali;LUO Jing;WANG Xuesong;WANG Youyan;YU Yiyi(Department of Pediatrics,Guizhou Medical University,Guiyang 550025,Guizhou,China;Department of Pediatrics,the Affiliated Hospital of Guizhou Medical University,Guiyang 550004,Guizhou,China)
出处
《贵州医科大学学报》
CAS
2020年第11期1360-1364,共5页
Journal of Guizhou Medical University
基金
贵州省卫生健康委科学技术基金项目(gzwjkj2020-1-141)。
关键词
婴儿
支气管肺炎
毛细支气管炎
人口学特征
临床特征
病原学特征
infant
bronchopneumonia
bronchiolitis
demographic characteristics
clinical characteristics
etiological characteristics
