摘要
目的探讨与分析在急性间质性肾炎治疗中免疫抑制剂的临床效果。方法抽选2017年6月至2019年8月在我院医治的急性间质性肾炎患者(138例)开展研究,随机数表法分成研究组与对照组,研究组69例,对照组69例。对照组行常规治疗方法,研究组在对照组基础上加上免疫抑制剂治疗,对比两组疗效和治疗后的肾功能指标。结果研究组血清β2微球蛋白低于对照组,差异显著,P<0.05。研究组24尿蛋白定量低于对照组,差异显著,P<0.05。研究组血肌酐低于对照组,差异显著,P<0.05。研究组血尿素氮低于对照组差异显著,P<0.05。研究组治疗总有效率高于对照组,差异显著,P<0.05。结论对于急性间质性肾炎患者来说,免疫抑制剂的治疗有效率高,且明显改善患者肾功能。
Objective to explore and analyze clinical effect of immunosuppressive agents in treatment of acute interstitial nephritis.Methods choose 138 cases acute interstitial nephritis patients in our hospital from June 2017 to August 2019 for research,divide them into study group and control group with random number table method,69 cases in study group and 69 cases in control group.Control group was treated with routine treatment,and study group was added with immunosuppressive therapy on the basis of control group.Compare effect and renal function indexes between two groups after treatment.Results serumβ2 microglobulin of study group was lower than control group,difference was significant,P<0.05.Quantitative urine protein of study group was lower than control group,difference was significant,P<0.05.Blood creatinine of study group was lower than control group,difference was significant,P<0.05.Blood urea nitrogen of study group was significantly lower than control group,P<0.05.Total effective rate in study group was higher than control group,difference was significant,P<0.05.Conclusion immunosuppressive therapy can improve renal function of acute interstitial nephritis patients effectively and significantly.
作者
吴琦
WUQi(Zhaotong City The First People's Hospital,Zhaotong,Yunnan 657000)
出处
《智慧健康》
2020年第24期177-178,共2页
Smart Healthcare
关键词
免疫抑制剂
急性间质性肾炎
临床效果
Immunosuppressant
Acute interstitial nephritis
Clinical effect
