摘要
目的探讨奥美拉唑治疗消化性溃疡伴发慢性胃炎的临床效果。方法选取2017年10月~2019年10月于我院就诊的200例消化性溃疡伴发慢性胃炎患者作为研究对象,采取随机数字表法将其分为观察组和对照组,每组各100例。所有患者给予基础药物治疗,对照组采用雷尼替丁治疗,观察组采用奥美拉唑治疗,比较两组的临床症状恢复时间、不良反应、治疗总有效率和溃疡愈合率。结果治疗后,观察组的腹部疼痛、嗳气、反酸、贫血、恶心呕吐的症状恢复时间短于对照组;观察组的不良反应总发生率率低于对照组;观察组的治疗总有效率为98%,高于对照组的77.00%,观察组的溃疡愈合率为82.00%,高于对照组的62.00%,差异均有统计学意义(P<0.05)。结论针对消化性溃疡伴发慢性胃炎患者采用奥美拉唑治疗,可有效缩短患者临床症状的恢复时间、降低不良反应发生率及提高治疗有效率和溃疡愈合率,取得良好的临床效果,适宜临床推广应用。
Objective To explore the clinical effect of Omeprazole in the treatment of peptic ulcer with chronic gastritis.Methods A total of 200 patients with peptic ulcer associated with chronic gastritis in our hospital from October 2017 to October 2019 were selected.They were divided into two groups by random number table method,and all patients were given basic medicationand,the control group was treated with Ranitidine,the observation group was treated with Omeprazole.The clinical symptoms recovery time,adverse reaction,total treatment efficiency and ulcer healing rate were compared between the two groups.Results After treatment,the recovery time of abdominal pain,belching,acid reflux,nemia,nausea and vomiting in the observation group was shorter than that in the control group;the total incidence rate of adverse reactions in the observation group was lower than that in the control group;the total efficiency of the observation group was 98.00%,higher than that in the control group of 77.00%,the ulcer healing rate of the observation group was 82.00%,which was higher than that of the control group of 62.00%,the differences were statistically significant(P<0.05).Conclusion The use of Omeprazole in patients with peptic ulcer accompanied by chronic gastritis can effectively shorten the recovery time of clinical symptoms,reduce the rate of adverse reactions,and improve the treatment efficiency and ulcer healing rate.It has achieved good clinical results and is suitable for clinical use.
作者
梁鹤
贺金云
LIANG He;HE Jin-yun(Department of Gastroenterology,Panjin Liaoyou Baoshihua Hospital,Liaoning Province,Panjin124010,China;Department of Hepatobiliary Pancreas Surgery,Panjin Liaoyou Baoshihua Hospital,Liaoning Province,Panjin124010,China)
出处
《中国当代医药》
2020年第31期56-58,共3页
China Modern Medicine
