摘要
为判定肾功能衰竭病原及引起的相关症状,并提供合理的诊治方案,本研究对一例柯基病犬进行表征、血常规、血液生化、血气及病原进行检测。结果显示,与正常参考值相比,病犬前期血常规检测中淋巴细胞比例(W-SCR)、中间细胞比例(W-MID)、中间细胞(MID)及红细胞分布宽度(RDW-CV)升高;粒细胞比例(W-LCR)、红细胞压积(PCV)、红细胞平均体积(MCV)、血红蛋白含量(MCH)、红细胞分布宽度(RDW-SD)明显降低。与正常参考值相比,生化指标中钙离子(Ca2+)、血糖(GLU)、尿素氮(BUN)、血磷(PHOS)、胰淀粉酶(AMYL)及肌酐(CRE)明显升高。血气指标中GLU、BUN、钾离子(K+)均比参考值高;钠离子(Na+)、氯离子(Cl-)、二氧化碳分压(PCO2)比参考值降低。犬钩端螺旋体抗原检测板检测结果为阳性。治疗后血常规中白细胞总数(WBC)、淋巴细胞(SCR)比正常参考值明显升高;红细胞总数(RBC)、血红蛋白(HGB)及血小板总数(PLT)则比参考值降低。经Hotelling T2对治疗前后各指标进行多变量分析,结果F=1905045.32,P=0.001,差异极显著;单变量检测指标中WBC、W-LCR、SCR、MID、HGB、PCV、MCV、RDW-SD差异极显著(P<0.01),W-MID、RBC、MCH及血小板分布宽度(PDW)差异显著(P<0.05)。治疗后生化检测指标中,与正常参考值相比,多数指标在正常值范围内。治疗后期病犬精神好转,经Hotelling T2与治疗前差异性分析,多变量F=85.21,P=0.081,差异不显著;单变量检验指标GLU、BUN、PHOS、AMYL及CRE差异极显著(P<0.01)。治疗后期血气指标中GLU、BUN、K+均比参考值高;Na+、Cl-及PCO2比参考值低,对治疗前后血气指标进行Hotelling T2差异性分析,多变量检验结果F=7978.48,P=0.008,差异极显著;单变量检验结果中,GLU和BUN差异极显著(P<0.01)。治疗方案中,采用利尿、抗生素药物,附加补充电解质、能量、维生素及CoA等综合输液治疗,7 d后,病犬精神好转,机体机能基本恢复正常,转归期部
To determine the pathogen and related symptoms caused by renal failure,and to provide a reasonable diagnosis and treatment plan,a case of disease on Welsh Corgi dog was tested by the method of symptoms,blood routine examination,blood biochemical test,blood gas analysis and identification of pathogen.The results showed that these data of W-SCR,W-MID,MID and RDW-CV rose than normal reference index in blood routine examination before the hospitalization,respectively.Meanwhile,data of W-LCR,PCV,MCV,MCH and RDW-SD had reduced separately.These data of Ca2+,GLU,BUN,PHOS,AMYL and CRE were up than normal reference index in blood biochemical test,respectively.These data of GLU,BUN and K+had risen respectively,nevertheless,these data of Na+,Cl-and PCO2 had lowered separately.The result was positive by the antigen testing with the Leptospira detector plate.After treatment with synthetical therapy,WBC and SCR had risen than normal references index,and data of RBC,HGB and PLT were down respectively.By the Hotelling T2 analysis of the difference between before and after the therapy on blood routine index,it was significant difference in the multivariate test(F=1905045.32,P=0.001).These data of WBC,W-LCR,SCR,MID,HGB,PCV,MCV and RDW-SD were extremely significant differences in single variable analysis(P<0.01),and other data with significant differences were W-MID,RBC,MCH and PDW(P<0.05).But,in blood biochemical test,most of data were in normal reference values.The mental state of sick dog was recovering gradually normal than before.Multivariate test was no significant difference by the Hotelling T2 analysis(F=85.21,P=0.081),but other data of GLU,BUN,PHOS,AMYL and CRE were extremely significantly different in single variable analysis(P<0.01).These data of GLU,BUN and K+were up than after therapy in blood gas analysis,and data of Na+,Cl-and PCO2 reduced respectively.There were extremely significant differences in the multivariate test(F=7978.48,P=0.008).These data with extremely significant differences were GLU and BUN in single va
作者
刘贵芳
田发益
LIU Guifang;TIAN Fayi(Animal Science College,Tibet Agriculture & Animal Husbandry University,Nyingchi 860000,China;Biotechnology Center,Tibet Agriculture &Animal Husbandry University,Nyingchi 860000,China)
出处
《中国畜牧兽医》
CAS
北大核心
2020年第11期3774-3782,共9页
China Animal Husbandry & Veterinary Medicine
基金
西藏农牧学院研究生教育创新计划项目(YJS2020-13)。
