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腹腔镜直肠癌根治术治疗高龄患者的疗效评价

Efficacy Evaluation of Laparoscopic Radical Resection of Rectal Cancer in Elderly Patients
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摘要 目的探索腹腔镜直肠癌根治术治疗高龄患者的疗效。方法选择2017年5月—2018年5月期间收治的100例高龄直肠癌患者为试验对象,采用数据库随机分为对照组和观察组,各50例,分别进行开腹手术治疗、腹腔镜直肠癌根治术治疗,随后对比两组各项指标。结果观察组CA199(25.65±3.19)U/mL、CEA(4.36±1.65)ng/mL、AFP(5.17±1.33)ng/mL、CRP(5.19±1.22)mg/L、并发症发生率(4.00%)、淋巴结转移数目(5.96±0.57)枚、淋巴结清扫数目(10.31±1.39)枚、手术时间(48.95±5.69)min、切口大小(2.37±0.17)cm、开始进食时间(12.19±5.85)h、肠鸣音恢复时间(29.37±5.52)h、肛门排气时间(10.18±2.52)d、腹胀持续时间(3.49±0.35)d均优于对照组(P<0.05)。结论对高龄直肠癌患者实施腹腔镜直肠癌根治术治疗效果显著,可发挥操作简便、安全性高、疗效高、术后并发症少、恢复快等特点,更利于病情康复,加速胃肠道功能恢复,降低手术风险,改善预后。 Objective To explore the curative effect of laparoscopic radical resection for rectal cancer in elderly patients.Methods From May 2017 to May 2018,100 elderly patients with rectal cancer were randomly divided into control group and observation group with 50 cases in each group.The patients were treated with open surgery and laparoscopic radical resection of rectal cancer,and then the indicators of the two groups were compared.Results In the observation group,CA199(25.65±3.19)U/mL,CEA(4.36±1.65)ng/mL,AFP(5.17±1.33)ng/mL,CRP(5.19±1.22)mg/L,complication rate(4.00%),number of lymph node metastasis(5.96±0.57),number of lymph node dissection(10.31±1.39),operation time(48.95±5.69)min,incision size(2.37±0.17)cm,time to start eating(12.19±5.85)h,the recovery time of wheezing(29.37±5.52)h,anal exhaust time(10.18±2.52)D and abdominal distension duration(3.49±0.35)d in the control group were better than those in the control group(P<0.05).Conclusion Laparoscopic radical resection of rectal cancer in elderly patients with rectal cancer has a significant effect,which can play the advantages of simple operation,high safety,high curative effect,less postoperative complications and rapid recovery,which is more conducive to the recovery of the disease,accelerate the recovery of gastrointestinal function,reduce the risk of surgery and improve the prognosis.
作者 唐元新 李晓霞 张德巍 TANG Yuanxin;LI Xiaoxia;ZHANG Dewei(Department of General Surgery,The Fourth Affiliated Hospital of China Medical University,Shenyang Liaoning 110032,China;The Fourth Clinical College Affiliated to China Medical University,Shenyang Liaoning 110032,China)
出处 《中国继续医学教育》 2020年第31期117-121,共5页 China Continuing Medical Education
基金 辽宁省高等学校基本科研项目(LFWK201712)。
关键词 腹腔镜 直肠癌根治术 高龄 手术安全性 临床推广 疗效评价 laparoscopy radical resection of rectal cancer advanced age surgical safety clinical promotion curative effect evaluation
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