摘要
目的探讨多巴胺联合硝普钠治疗心肌梗死后左心衰竭40例的临床效果。方法纳入我院于2017年1月至2018年12月收治的40例心肌梗死后左心衰竭患者为研究对象。采用随机数字表分组,其中对照组选择多巴胺治疗,研究组则选择多巴胺联合硝普钠治疗。比对两组患者心力衰竭纠正日数、NYHA分级改善2级日数、总住院天数、治疗的效果,施治前后患者左心室射血分数、心功能等级、生活质量,并发症发生率。结果研究组患者疗效比对照组高,P <0.05。其中,对照组治愈10例,无好转4例,有效6例,总有效率是80%;研究组治愈16例,无好转0例,有效4例,总有效率是100%。施治前两组左心室射血分数、心功能等级、生活质量相近,P> 0.05;施治后研究组左心室射血分数、心功能等级、生活质量改善的程度更大,P <0.05。研究组心力衰竭纠正日数、NYHA分级改善2级日数、总住院天数更有优势,P <0.05,结论多巴胺联合硝普钠治疗心肌梗死后左心衰竭的疗效比较好,有利于患者病情的消除和生存质量的提升,且心功能有了明显改善,安全性高。
Objective To investigate the clinical eff ect of dopamine combined with sodium nitroprusside in the treatment of 40 cases of left heart failure after myocardial infarction.Methods Forty patients with left heart failure after myocardial infarction in our hospital from January 2017 to December 2018 were enrolled.The patients were randomly divided into two groups:the control group was treated with dopamine and the study group was treated with dopamine combined with sodium nitroprusside.Compared between the two groups the days of correction of heart failure,the days of NYHA grade improvement,the total days of hospitalization,the effect of treatment,the left ventricular ejection fraction,the grade of cardiac function,the quality of life and the incidence of complications.Results The curative effect of the study group was higher than that of the control group(P<0.05).Among them,the control group cured 10 cases,no improvement in 4 cases,eff ective in 6 cases,the total effective rate was 80%;the study group cured 16 cases,no improvement in 0 case,effective in 4 cases,the total eff ective rate was 100%.The left ventricular ejection fraction,cardiac function grade and quality of life of the two groups were similar before treatment(P>0.05),and the left ventricular ejection fraction,cardiac function grade and quality of life of the study group were improved more significantly after treatment(P<0.05).In the study group,the days of correction of heart failure,the days of improvement of NYHA grade 2 and the total days of hospitalization were more advantageous,P<0.05.Conclusion Dopamine combined with sodium nitroprusside is effective in the treatment of left heart failure after myocardial infarction,which is benefi cial to the elimination of the condition and the improvement of quality of life,and the cardiac function is obviously improved and the safety is high.
作者
张仁辉
ZHANG Renhui(The Third People's Hospital of Benxi County,Benxi 117104,China)
出处
《中国医药指南》
2020年第28期95-96,共2页
Guide of China Medicine
关键词
心肌梗死后左心衰竭
多巴胺
硝普钠
临床效果
Left heart failure after myocardial infarction
Dopamine
Sodium nitroprusside
Clinical effect
