摘要
目的探究脑挫裂伤开颅术后意识障碍患者采用神经节苷脂联合高压氧治疗的临床疗效。方法选取该院2016年1月—2019年11月收治的84例脑挫裂伤开颅术后意识障碍患者为研究对象,按照随机数字表法分为两组,对照组仅行高压氧治疗,观察组于对照组基础上采用神经节苷脂治疗,对比两组治疗前、治疗1周、2周以及4周后的GCS(格拉斯哥昏迷)评分、并发症发生情况。结果观察组治疗1周、治疗2周、治疗3周后的GCS评分分别为(10.85±0.63)分、(11.58±0.98)分、(12.85±0.63)分,均高于对照组(t=12.696、15.663、20.158,P<0.05);观察组并发症发生率为9.52%,低于对照组(χ^2=3.977,P<0.05)。结论脑挫裂伤开颅术后意识障碍患者采用神经节苷脂联合高压氧治疗的效果理想,安全性高。
Objective To explore the clinical efficacy of ganglioside combined with hyperbaric oxygen therapy in patients with consciousness disorder after brain contusion and laceration.Methods A total of 84 patients with impaired consciousness after brain contusion and laceration in the hospital from January 2016 to November 2019 were selected as the research objects.They were divided into two groups according to a random number table.The control group received only hyperbaric oxygen therapy.The observation group was treated with gangliosides on the basis of the control group,and the GCS(Glasgow coma)scores and complications of the two groups before treatment,1 week,2 weeks,and 4 weeks after treatment were compared.Results The GCS scores of the observation group after 1 week of treatment,2 weeks of treatment,and 3 weeks of treatment were(10.85±0.63)points,(11.58±0.98)points,and(12.85±0.63)points,which were higher than those of the control group(t=12.696,15.663,20.158,P<0.05);the complication rate of the observation group was 9.52%,which was lower than that of the control group(χ^2=3.977,P<0.05).Conclusion The treatment of gangliosides combined with hyperbaric oxygen therapy for patients with impaired consciousness after brain contusion and laceration is satisfactory and safe.
作者
杨超
管峥峰
雷鹏
YANG Chao;GUAN Zheng-feng;LEI Peng(Department of Neurosurgery,Liyang Traditional Chinese Medicine Hospital,Liyang,Jiangsu Province,213300 China)
出处
《系统医学》
2020年第20期71-73,共3页
Systems Medicine
关键词
脑挫裂伤
开颅术
意识障碍
神经节苷脂
高压氧
联合治疗
Brain contusion and laceration
Craniotomy
Disturbance of consciousness
Ganglioside
Hyperbaric oxygen
Combined therapy
