摘要
目的:评估新生儿心脏术后早期喂养充分性与住院期间预后的关系。方法:回顾性分析了2015年至2017年广东省人民医院232例体外循环辅助下行心脏外科手术的新生病儿资料,收集记录每日喂养量及住院期间的临床资料和预后事件。结果:以术后一周内的任一天喂养量是否达到120 mL/kg,将新生病儿分为充分喂养组(≥120 mL/kg)和未充分喂养组(<120 mL/kg)。多变量分析显示,充分喂养组术后机械通气时间减少了62.8 h(β=-62.8,95%CI:-108.9~16.7,P=0.008);术后住院时间减少了8.1 d(β=-8.1,95%CI:-14~2.1,P=0.008);住院不良预后风险下降了70%(OR=0.3,95%CI:0.13~0.72,P=0.007)。结论:新生儿心脏术后早期充分喂养与良好的住院预后有关。
Objective:To explore the association between early adequate enteral feeding and hospital outcomes following neonatal cardiopulmonary bypass surgery.Methods:We retrospectively reviewed records of 232 neonates who underwent congenital heart surgery requiring cardiopulmonary bypass from 2015 to 2017 at Guangdong Provincial People’s Hospital.Data on feeding amount and postoperative variables were collected.Study outcomes included mortality,hospital length of stay,duration of mechanical ventilation,and adverse prognostic risks.Results:Neonates were separated into adequate feeding group[received a max feeding amount of≥120 mL/(kg·d)]and inadequate feeding group[<120 mL/(kg·d)],according to the dailly feeding amount within one week after operation.In multivariable analysis,adequate feeding group was associated with a significantly decreased duration of mechanical ventilation(β=-62.8 hours,95%CI:-108.9^-16.7,P=0.008)and length of stay in the hospital(β=-8.1 days,95%CI:-14^-2.1,P=0.008).Adequate feeding group was also associated with a significant decrease in adverse prognostic risks(OR=0.3,95%CI:0.13~0.72,P=0.007).Conclusion:Early adequate feeding to neonates after cardiac surgery was associated with better outcomes during hospital.
作者
张崇健
孙新
李柳苑
曾晓东
李晓峰
罗丹东
ZHANG Chong-jian;SUN Xin;LI Liu-yuan;ZENG Xiao-dong;LI Xiao-feng;LUO Dan-dong(Department of Intensive Care Unit of Cardiovascular Surgery,Guangdong Academy of Medical Sciences,Guangzhou 510080,Guangdong,China;Department of NICU,Guangdong Cardiovascular Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,Guangdong,China)
出处
《肠外与肠内营养》
CSCD
北大核心
2020年第5期280-284,共5页
Parenteral & Enteral Nutrition
基金
广东省医学科学技术研究基金项目(A2019445)。
关键词
心脏手术
先天性心脏病
预后
肠内营养
新生儿
Cardiac surgery
Congenital heart disease
Outcomes
Enteral nutrition
Neonate
