摘要
肠道微生物稳态是人体阴阳平衡的重要保障,亦是脾功能正常的重要保障。"阳微阴弦"最早出自《金匮要略·胸痹心痛短气病脉证治》篇,即阳气衰微,既而阴邪上乘。"阳微"即为本虚,如脾气亏虚;"阴弦"即是标实,如痰浊、血瘀等因水液代谢障碍而致病理产物。脾虚运化失常,肠道微生物稳态失衡,导致痰瘀互结壅遏脉道,从而导致动脉粥样硬化的发生。因此,从肠道微生物稳态失衡对动脉粥样硬化的影响解析"阳微阴弦"的现代生物学内涵具有重要意义。
Intestinal microbial homeostasis is an important guarantee for the balance of Yin and Yang in human body,and also an important guarantee for the normal spleen function."Yangwei Yinxian"first came from Jingui Yaolue,that is,there is Yang Qi deficiency and then Yin evils would attack."Yangwei"means root deficiency,such as the deficiency of spleen Qi."Yinxian"is the branch excess,such as phlegm,blood stasis and other disorders caused by water and fluid metabolism products.Spleen deficiency,abnormal circulation and transformation,and imbalance of intestinal microbial homeostasis lead to the mutual accumulation of phlegm and blood stasis in the vessels,and thus leading to the occurrence of atherosclerosis.Therefore,it is of great significance to analyze the modern biological connotation of"Yang wei Yin xian"from the influence of intestinal microbial homeostasis imbalance on atherosclerosis.
作者
王杰
贾连群
宋囡
吴瑶
陈丝
曹媛
王莹
曹慧敏
吕晓明
付鑫
WANG Jie;JIA Lianqun;SONG Nan;WU Yao;CHEN Si;CAO Yuan;WANG Ying;CAO Huimin;LYU Xiaoming;FU Xin(Craduate School,Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Key Laboratory of Ministry of Education for TCM Viscera-State Theory and Applications of Major Scientific Research Platiorm,Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)
出处
《中华中医药学刊》
CAS
北大核心
2020年第9期182-185,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金(81974548)
辽宁省自然科学基金指导计划(20180550767,2019-ZD-0966)
中医脏象理论及应用教育部重点实验室开放基金(ZYZX1703)。
关键词
肠道微生物稳态
动脉粥样硬化
阳微阴弦
本虚标实
intestinal microbial homeostasis
atherosclerosis
Yangwei Yinxian
root deficiency and branch excess
