摘要
目的探讨脑梗死患者颈总动脉血流动力学参数与颈内动脉狭窄程度的相关性。方法收集苏州大学附属常熟医院重症监护室2017年1月至2019年12月收治的60例脑梗死患者的临床资料,均存在颈内动脉颅内段病变,依据头颈血管超声检查结果,将颈内动脉中度及重度狭窄者44例纳入狭窄组,颈内动脉闭塞者16例纳入闭塞组。检测颈总动脉血流动力学参数,记录血流量(BFV)、血管内径(D)、阻力指数(RI)、舒张末期血流速度(EDV)、收缩期血流峰值(PSV),并分析其与颈内动脉狭窄程度的相关性。结果两组健侧颈总动脉血流动力学参数比较差异未见统计学意义(P>0.05),两组患侧D及PSV比较差异未见统计学意义(P>0.05)。与健侧相比,两组患侧RI较高,BFV及EDV均较低,差异有统计学意义(P<0.05);与狭窄组相比,闭塞组患侧RI较高,BFV及EDV均较低,差异有统计学意义(P<0.05)。Logistic回归结果显示,颈总动脉血流动力学参数RI、BFV、EDV与颈内动脉狭窄程度密切相关(P<0.05),得到Logistic回归方程:Y=-7.398+7.928X1-0.010X2-0.439X3。结论脑梗死患者颈内动脉狭窄程度与颈总动脉RI、BFV及EDV有关,可作为颈内动脉狭窄的辅助检查指标。
Objective To investigate the correlation between hemodynamic parameters of the common carotid artery and the degree of internal carotid artery stenosis in patients with cerebral infarction.Methods The clinical data of 60 patients with cerebral infarction who were hospitalized by Intensive Care Unit of Changshu Hospital Affiliated to Soochow University from January 2017 to December 2019 were collected.All of them had internal carotid artery intracranial lesions.According to the results of head and neck vascular ultrasound examination,the 44 patients with moderate and severe stenosis were included in the stenosis group,and 16 patients with internal carotid artery occlusion were included in the occlusion group.The hemodynamic parameters of the common carotid artery were tested,and then,blood flow(BFV),inner diameter of blood vessel(D),resistance index(RI),end-diastolic blood flow velocity(EDV),and peak systolic blood flow(PSV)were recorded.The correlations of these hemodynamic parameters with the degree of carotid artery stenosis were analyzed.Results There was no significant difference in the hemodynamic parameters of the healthy side of the common carotid artery between the two groups(P>0.05),and there was no significant difference in the D and PSV of the diseased side between the two groups(P>0.05).Compared with the healthy side,the RI of the diseased side was higher,and the BFV and EDV of the diseased side were lower in both groups(P<0.05).Compared with the stenosis group,the RI of the diseased side of the occlusion group was higher,and the BFV and EDV were lower(P<0.05).Logistic regression showed that RI,BFV and EDV were closely related to the degree of internal carotid artery stenosis(P<0.05),and the Logistic regression equation was obtained:Y=-7.398+7.928X1-0.010X2-0.439X3.Conclusions The degree of internal carotid artery stenosis in patients with cerebral infarction is related to the hemodynamic parameters,such as RI,BFV and EDV,which can be used as auxiliary indicators for diagnosis of internal carotid arte
作者
阳亮
叶宏伟
范佳
许春阳
Yang Liang;Ye Hongwei;Fan Jia;Xu Chunyang(Department of Intensive Care Unite,Changshu Hospital Affiliated to Soochow University,Changshu 215500,China)
出处
《中国实用医刊》
2020年第19期52-55,共4页
Chinese Journal of Practical Medicine
关键词
脑梗死
颈总动脉
血流动力学参数
颈内动脉狭窄
相关性
Cerebral infarction
Common carotid artery
Hemodynamic parameters
Internal carotid artery stenosis
Correlation
