摘要
目的分析不同梅毒血清学试验在孕产妇梅毒诊断中的应用效果。方法选择2017年6月至2018年7月于我院确诊为梅毒的80例孕产妇的血清标本作为观察样本,分别采用甲苯胺红不加热血清试验(Trust)、梅毒螺旋体明胶凝集试验(TPPA)进行检测。对两种不同检测方法对孕产妇梅毒诊断的准确度、特异度、灵敏度进行判定和比较。结果TPPA诊断孕产妇梅毒的准确度、特异度、灵敏度分别为97.50%、96.25%、93.75%,均明显高于Trust的75.00%、66.25%、68.75%,差异具有统计学意义(P<0.05)。结论Trust、TPPA对孕产妇梅毒筛查均具有良好的诊断价值,且两种梅毒血清学检验方法的优势和缺点各有不同,临床可根据不同的检验目的并结合患者的临床症状表现,对梅毒血清学试验方法进行合理选择。
Objective To analyze the application effect of different syphilis serological tests in the diagnosis of syphilis in pregnant women.Methods Serum samples of 80 pregnant women who were diagnosed with syphilis in our hospital from June 2017 to July 2018 were selected as observation samples.Toluidine red untreated serum test(Trust)and treponema pallidum particle agglutination assay(TPPA)were used for detection respectively.The accuracy,specificity and sensitivity of two different detection methods for diagnosis of pregnant women syphilis were judged and compared.Results The accuracy,specificity,and sensitivity of TPPA in diagnosing pregnant women syphilis were 97.50%,96.25%and 93.75%respectively,which were significantly higher than 75.00%,66.25%and 68.75%of Trust,and the difference was statistically significant(P<0.05).Conclusion Both Trust and TPPA have good diagnostic value for syphilis screening in pregnant women,and the advantages and disadvantages of the two methods of serological test for syphilis are different.The serological test methods of syphilis can be reasonably selected according to different testing purposes and combined with the clinical symptoms of patients.
作者
于洪帅
YU Hongshuai(Dalian Maternal and Child Health Hospital,Dalian 116021,China)
出处
《中国医药指南》
2020年第27期47-48,共2页
Guide of China Medicine
关键词
梅毒
孕产妇
甲苯胺红不加热血清试验
梅毒螺旋体明胶凝集试验
诊断价值
Syphilis
Pregnant women
Toluidine red untreated serum test
Treponema pallidum particle agglutination assay
Diagnostic value
