摘要
目的:探讨重复经颅磁刺激在降低抑郁症患者焦虑抑郁症状及尼古丁渴求中的应用效果。方法:选择2018年12月-2019年6月于赣州市某三级甲等医院门诊和住院治疗的抑郁症患者60例。采用随机数字表法分为对照组和研究组,每组30例。研究组采取重复经颅磁刺激治疗,对照组则采取假性刺激治疗,疗程4周,随访16周。比较两组焦虑抑郁程度、尼古丁依赖程度及吸烟渴求程度。结果:治疗前,两组汉密顿焦虑量表(HAMA)、汉密顿抑郁量表(HAMD-17)、尼古丁依赖严重程度检验量表(FTND)、吸烟渴求视觉模拟量表(VAS)、失眠严重指数量表(ISI)评分比较,差异均无统计学意义(P>0.05);治疗后,两组HAMA、HAMD-17、FTND、VAS、ISI评分均低于治疗前,且研究组均低于对照组,差异均有统计学意义(P<0.05)。结论:抑郁症患者采取重复经颅磁刺激治疗效果显著,能够改善患者焦虑抑郁程度,减轻尼古丁渴求度,改善患者睡眠质量。
Objective:To explore the application effect of repetitive transcranial magnetic stimulation in reducing anxiety and depression symptoms and nicotine craving in patients with depression.Method:A total of 60 patients with depression were selected from the outpatient and inpatient treatment in tertiary class A hospital of Ganzhou City from December 2018 to June 2019.They were divided into control group and study group by random number table method,30 cases in each group.The study group was treated with repeated transcranial magnetic stimulation,while the control group was treated with sham stimulation,the course of treatment was 4 weeks,followed up for 16 weeks.The levels of anxiety and depression,nicotine dependence and cigarette craving were compared between the two groups.Result:Before treatment,there were no significant differences in the Hamilton anxiety scale (HAMA),Hamilton depression scale (HAMD-17),fagerstrom test of nicotine dependence (FTND),visual analogue scale (VAS) for smoking craving,and insomnia severity index (ISI) between the two groups (P>0.05).After treatment,HAMA,HAMD-17,FTND,VAS,ISI scores of the two groups were lower than those before treatment,and those of the study group were lower than those of the control group,the differences were statistically significant (P<0.05).Conclusion:The effect of repetitive transcranial magnetic stimulation on depression is remarkable,it can improve the degree of anxiety and depression,reduce nicotine craving and improve sleep quality.
作者
廖院平
吴丽萍
陈方
唐斯伟
LIAO Yuanping;WU Liping;CHEN Fang;TANG Siwei(The Third People’s Hospital of Ganzhou City,Ganzhou 341000,China)
出处
《中国医学创新》
CAS
2020年第26期160-163,共4页
Medical Innovation of China
基金
江西省卫生健康委员会科技计划项目(20204676)
赣州市卫生和计划生育委员会科研计划项目(2019-2-42)。
关键词
抑郁症
重复经颅磁刺激
焦虑抑郁
尼古丁渴求
睡眠质量
Depression
Repetitive transcranial magnetic stimulation
Anxiety and depression
Nicotine craving
Sleep quality
